Title:
CHLORITE IN THE TREATMENT OF NEURODEGENERATIVE DISEASE
Document Type and Number:
WIPO Patent Application WO2005076819
Kind Code:
A3
Abstract:
The invention features methods of treating a macrophage-associated neurodegenerative disease such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), or multiple sclerosis (MS) in a subject by administering chlorite in an amount effective to decrease blood immune cell activation. The invention also features methods of monitoring therapy by assessing blood immune cell activation before and after therapy.
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Inventors:
MCGRATH MICHAEL S (US)
Application Number:
PCT/US2005/002469
Publication Date:
April 13, 2006
Filing Date:
January 25, 2005
Export Citation:
Assignee:
UNIV CALIFORNIA (US)
MCGRATH MICHAEL S (US)
MCGRATH MICHAEL S (US)
International Classes:
A61K33/00; (IPC1-7): A61K33/00; A61K33/14; A61K33/40; A61P25/00; A61P25/28
Foreign References:
| US4725437A | 1988-02-16 |
Other References:
MILLER T.M. ET AL: "Treating Neurodegenerative Diseases with Antibiotics", SCIENCE, vol. 307, January 2005 (2005-01-01), pages 361 - 362, XP002994599
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