Title:
CHOLESTEROL-MODIFIED HYALURONIC ACIDS
Document Type and Number:
WIPO Patent Application WO/2024/030660
Kind Code:
A3
Abstract:
Disclosed herein are cholesterol-modified hyaluronic acid polymers, as well as methods of making and using thereof.
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Inventors:
SONG JIE (US)
CHANG SHING-YUN (US)
CHANG SHING-YUN (US)
Application Number:
PCT/US2023/029566
Publication Date:
March 14, 2024
Filing Date:
August 04, 2023
Export Citation:
Assignee:
UNIV MASSACHUSETTS (US)
International Classes:
C07C13/66; A61K9/14; A61K31/728
Foreign References:
| US20140221418A1 | 2014-08-07 | |||
| US20150086615A1 | 2015-03-26 |
Other References:
LIN CHIH-AN, HO HUI-MIN, VENKATESAN PARTHIBAN, HUANG CHIUNG-YI, CHENG YU-JHEN, LIN YU-HSING, LIN HUA-YANG, CHEN TZU-YANG, HUANG MI: "Hyaluronic Acid-Glycine-Cholesterol Conjugate-Based Nanoemulsion as a Potent Vaccine Adjuvant for T Cell-Mediated Immunity", PHARMACEUTICS, vol. 13, no. 10, 27 September 2021 (2021-09-27), CH , pages 1 - 15, XP093149404, ISSN: 1999-4923, DOI: 10.3390/pharmaceutics13101569
ZHU ZHIHONG, LI DONGYANG, LI YUENAN, YANG XINGGANG, PAN WEISAN: "In vitro–in vivo evaluation of hyaluronic acid-based amphiphilic copolymers for tumour targeted delivery: the role of hydrophobic groups", RSC ADVANCES, vol. 7, no. 39, 1 January 2017 (2017-01-01), GB , pages 23942 - 23953, XP093149409, ISSN: 2046-2069, DOI: 10.1039/C7RA03211K
ZHU ZHIHONG, LI DONGYANG, LI YUENAN, YANG XINGGANG, PAN WEISAN: "In vitro–in vivo evaluation of hyaluronic acid-based amphiphilic copolymers for tumour targeted delivery: the role of hydrophobic groups", RSC ADVANCES, vol. 7, no. 39, 1 January 2017 (2017-01-01), GB , pages 23942 - 23953, XP093149409, ISSN: 2046-2069, DOI: 10.1039/C7RA03211K
Attorney, Agent or Firm:
ZUCCHERO, Anthony J. et al. (US)
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