Title:
CHROMANE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2013/181202
Kind Code:
A3
Abstract:
The present invention provides a compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for preventing or treating diseases or conditions associated with and/or mediated by β-secretase activity, hydrolysis of a β-secretase site of a β -amyloid precursor protein, and/or β -amyloid protein accumulation, including a pharmaceutical composition for preventing or treating diseases including, but not limited to, Glaucoma, MCI (Mild cognitive impairment) or Alzheimer's disease, especially, Alzheimer's disease.
Inventors:
MUNAKATA RYOSUKE (JP)
INOUE MAKOTO (JP)
TOMINAGA HIROAKI (JP)
YAMASAKI SHINGO (JP)
SHIINA YASUHIRO (JP)
SAMIZU KIYOHIRO (JP)
HAMAGUCHI HISAO (JP)
HONG LIN (US)
INOUE MAKOTO (JP)
TOMINAGA HIROAKI (JP)
YAMASAKI SHINGO (JP)
SHIINA YASUHIRO (JP)
SAMIZU KIYOHIRO (JP)
HAMAGUCHI HISAO (JP)
HONG LIN (US)
Application Number:
PCT/US2013/043016
Publication Date:
January 30, 2014
Filing Date:
May 29, 2013
Export Citation:
Assignee:
ASTELLAS PHARMA INC (JP)
COMENTIS INC (US)
COMENTIS INC (US)
International Classes:
A61K31/352; C07D263/52
Domestic Patent References:
WO2011072064A1 | 2011-06-16 |
Foreign References:
US20110152253A1 | 2011-06-23 | |||
US20110218192A1 | 2011-09-08 | |||
US20100087429A1 | 2010-04-08 | |||
US20120065195A1 | 2012-03-15 |
Other References:
See also references of EP 2854797A4
Attorney, Agent or Firm:
BOLIN, Kimberly, A. et al. (755 Page Mill RoadPalo Alto, CA, US)
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