Title:
CHROMATOGRAPHIC SYSTEM FOR NUCLEIC ACID DETECTION
Document Type and Number:
WIPO Patent Application WO/2011/008030
Kind Code:
A2
Abstract:
The present invention relates to a strip for detecting nucleic acids in analysis samples, based on the principles of lateral motion development technique and sequence-specific hybridization of nucleic acids, and to a nucleic acid detection system comprising the strip and also to a specific nucleic acid detection method employing the strip. The strip, system and method of the present invention allow not only a very high degree of ease in use but also of detection sensitivity and specificity, and allow accurate and rapid analysis even when a small amount of nucleic acid is employed.
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Inventors:
CHOI EUI-YUL (KR)
NAHM KIE-BONG (KR)
JEONG DONG-SEOK (KR)
KIM SUNG-JOONG (KR)
NAHM KIE-BONG (KR)
JEONG DONG-SEOK (KR)
KIM SUNG-JOONG (KR)
Application Number:
PCT/KR2010/004598
Publication Date:
January 20, 2011
Filing Date:
July 15, 2010
Export Citation:
Assignee:
BODITECHMED INC (KR)
CHOI EUI-YUL (KR)
NAHM KIE-BONG (KR)
JEONG DONG-SEOK (KR)
KIM SUNG-JOONG (KR)
CHOI EUI-YUL (KR)
NAHM KIE-BONG (KR)
JEONG DONG-SEOK (KR)
KIM SUNG-JOONG (KR)
International Classes:
C12Q1/68; G01N30/90; G01N33/50
Foreign References:
| KR100639776B1 | 2006-10-27 |
Other References:
GISSMANN L; BOSHART M; DURST M; IKENBERG H; WAGNER D; HAUSEN H.: "Presence of human papillomavirus in genital tumors", J INVEST DERMATOL, vol. 83, no. 1, 1984, pages 26S - 8S
DE VILLIERS EM.: "Heterogeneity of the human papillomavirus group", J VIROL, vol. 63, 1989, pages 4898 - 903
LORINCZ AT; REID R; JENSON AB; GREENBERG MD; LANCASTER W; KURMAN RJ: "Human papillomavirus infection of the cervix: relative risk association of 15 common anogental types", OBSTET GYNECOL, vol. 79, 1992, pages 328 - 37
MCINDOE WA ET AL., OBSTETRICS AND GYNAECOLOGY, vol. 64, no. 4, October 1984 (1984-10-01), pages 451 - 458
DUGGAN MA; BENOIT JL; MCGREGOR SE; NATION JG; INOUE M; STUART GC: "The human papillomavirus status of 114 endocervical adenocarcinoma cases by dot-blot hybridization", HUM PATHOL, vol. 189, 1993, pages 12 - 9
JANE C. STERLING; STEPHEN K. TYING: "Human Papillomavirus: Clinical and scientific advances", ARNOLD, 2001
SCHNEIDER A; ZAHM DM; KIRCHMAYR R; SCHNEIDER VL: "Screening for cervical intraepithelial neoplasia grade 2/3: validity of cytologic study, cervicography, and human papillomavirus detection", AM J OBSTET GYNECOL, vol. 174, 1996, pages 1534 - 41, XP005691262, DOI: doi:10.1016/S0002-9378(96)70602-6
CUZICK J; BEVERLEY E; HO L; TERRY G; SAPPER H; MIELZYNSKA I ET AL.: "HPV testing in primary screening of older women", BR J CANCER, vol. 81, 1999, pages 554 - 8
"LABORATORY TECHNIQUES IN BIOCHEMISTRY AND MOLECULAR BIOLOGY", vol. 15, 1985, ELSEVIER, pages: 318 - 322
"Molecular Cloning: A Laboratory Manual", 2001, HARBOR LABORATORY PRESS
"Short Protocols in Molecular Biology", 1999, JOHN WILEY &SONS
"DNA Cloning", vol. I, II, 1985
"Oligonucleotide Synthesis", 1984
"Nucleic Acid Hybridization", 1984
"Transcription And Translation", 1984
"Culture Of Animal Cells", 1987, FRESHNEY AND ALAN, LISS, INC.
"Gene Transfer Vectors for Mammalian Cells"
"Current Protocols in Molecular Biology and Short Protocols in Molecular Biology"
"Recombinant DNA Methodology", ACADEMIC PRESS
"Gene Transfer Vectors For Mammalian Cells", 1987, COLD SPRING HARBOR LABORATORY
"Methods In Enzymology", vol. 154, 155
"Immobilized Cells And Enzymes", 1986, IRL PRESS
PERBAL: "A Practical Guide To Molecular Cloning", 1984
"Methods In Enzymology", ACADEMIC PRESS, INC.
"Immunochemical Methods In Cell And Molecular Biology", 1987, ACADEMIC PRESS
"Handbook Of Experimental Immunology", 1986, article "I-IV"
BOLLAG ET AL.: "Protein Methods", 1996, JOHN WILEY &SONS
"Immunology Methods Manual", 1997, ACADEMIC PRESS
DOYLE; GRIFFITHS: "Cell and Tissue Culture: Laboratory Procedures in Biotechnology", 1998, JOHN WILEY &SONS
JIANDUAN LI ET AL.: "Denaturing High-Performance Liquid Chromatography for Detecting and Typing Genital Human Papillomavirus", J OF CLINICAL MICROBIOLOGY, vol. 41, no. 4, 2003, pages 5563 - 5571
A J VAN DEN BRULE ET AL., JOURNAL OF CLINICAL MICROBIOLOGY, vol. 28, no. 12, 1990, pages 2739 - 2743
ANA-MARIA DE RODA HUSMAN ET AL., JOURNAL OF GENERAL VIROLOGY, vol. 76, 1995, pages 1057 - 1062
ANA-MARIA DE RODA HUSMAN ET AL.: "The use of general primers GP5 and GP6 elongated at their 3' ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR", J. OF GENERAL VIROLOGY, vol. 76, 1995, pages 1057 - 62, XP002921802
P.E. GRAVITT ET AL.: "Improved amplification of genital human papillomaviruses", J OF CLINICAL MICROBIOLOGY, vol. 38, no. 1, 2000, pages 357 - 61, XP002490517
BERNHARD KLETER ET AL.: "Novel short-fragment PCR assay for highly sensitive broad-spectrum detection of anogenital human papillomaviruses", AMERICAN J OF PATHOLOGY, vol. 153, no. 6, 1998, pages 1731 - 9, XP002100812
PETER J. F. SNIJDERS ET AL.: "The use of general primers in the polymerase chain reaction permits the detection of a broad spectrum of human papillomavirus genotypes", J OF GENERAL VIROLOGY, vol. 71, 1990, pages 173 - 81
See also references of EP 2455487A4
DE VILLIERS EM.: "Heterogeneity of the human papillomavirus group", J VIROL, vol. 63, 1989, pages 4898 - 903
LORINCZ AT; REID R; JENSON AB; GREENBERG MD; LANCASTER W; KURMAN RJ: "Human papillomavirus infection of the cervix: relative risk association of 15 common anogental types", OBSTET GYNECOL, vol. 79, 1992, pages 328 - 37
MCINDOE WA ET AL., OBSTETRICS AND GYNAECOLOGY, vol. 64, no. 4, October 1984 (1984-10-01), pages 451 - 458
DUGGAN MA; BENOIT JL; MCGREGOR SE; NATION JG; INOUE M; STUART GC: "The human papillomavirus status of 114 endocervical adenocarcinoma cases by dot-blot hybridization", HUM PATHOL, vol. 189, 1993, pages 12 - 9
JANE C. STERLING; STEPHEN K. TYING: "Human Papillomavirus: Clinical and scientific advances", ARNOLD, 2001
SCHNEIDER A; ZAHM DM; KIRCHMAYR R; SCHNEIDER VL: "Screening for cervical intraepithelial neoplasia grade 2/3: validity of cytologic study, cervicography, and human papillomavirus detection", AM J OBSTET GYNECOL, vol. 174, 1996, pages 1534 - 41, XP005691262, DOI: doi:10.1016/S0002-9378(96)70602-6
CUZICK J; BEVERLEY E; HO L; TERRY G; SAPPER H; MIELZYNSKA I ET AL.: "HPV testing in primary screening of older women", BR J CANCER, vol. 81, 1999, pages 554 - 8
"LABORATORY TECHNIQUES IN BIOCHEMISTRY AND MOLECULAR BIOLOGY", vol. 15, 1985, ELSEVIER, pages: 318 - 322
"Molecular Cloning: A Laboratory Manual", 2001, HARBOR LABORATORY PRESS
"Short Protocols in Molecular Biology", 1999, JOHN WILEY &SONS
"DNA Cloning", vol. I, II, 1985
"Oligonucleotide Synthesis", 1984
"Nucleic Acid Hybridization", 1984
"Transcription And Translation", 1984
"Culture Of Animal Cells", 1987, FRESHNEY AND ALAN, LISS, INC.
"Gene Transfer Vectors for Mammalian Cells"
"Current Protocols in Molecular Biology and Short Protocols in Molecular Biology"
"Recombinant DNA Methodology", ACADEMIC PRESS
"Gene Transfer Vectors For Mammalian Cells", 1987, COLD SPRING HARBOR LABORATORY
"Methods In Enzymology", vol. 154, 155
"Immobilized Cells And Enzymes", 1986, IRL PRESS
PERBAL: "A Practical Guide To Molecular Cloning", 1984
"Methods In Enzymology", ACADEMIC PRESS, INC.
"Immunochemical Methods In Cell And Molecular Biology", 1987, ACADEMIC PRESS
"Handbook Of Experimental Immunology", 1986, article "I-IV"
BOLLAG ET AL.: "Protein Methods", 1996, JOHN WILEY &SONS
"Immunology Methods Manual", 1997, ACADEMIC PRESS
DOYLE; GRIFFITHS: "Cell and Tissue Culture: Laboratory Procedures in Biotechnology", 1998, JOHN WILEY &SONS
JIANDUAN LI ET AL.: "Denaturing High-Performance Liquid Chromatography for Detecting and Typing Genital Human Papillomavirus", J OF CLINICAL MICROBIOLOGY, vol. 41, no. 4, 2003, pages 5563 - 5571
A J VAN DEN BRULE ET AL., JOURNAL OF CLINICAL MICROBIOLOGY, vol. 28, no. 12, 1990, pages 2739 - 2743
ANA-MARIA DE RODA HUSMAN ET AL., JOURNAL OF GENERAL VIROLOGY, vol. 76, 1995, pages 1057 - 1062
ANA-MARIA DE RODA HUSMAN ET AL.: "The use of general primers GP5 and GP6 elongated at their 3' ends with adjacent highly conserved sequences improves human papillomavirus detection by PCR", J. OF GENERAL VIROLOGY, vol. 76, 1995, pages 1057 - 62, XP002921802
P.E. GRAVITT ET AL.: "Improved amplification of genital human papillomaviruses", J OF CLINICAL MICROBIOLOGY, vol. 38, no. 1, 2000, pages 357 - 61, XP002490517
BERNHARD KLETER ET AL.: "Novel short-fragment PCR assay for highly sensitive broad-spectrum detection of anogenital human papillomaviruses", AMERICAN J OF PATHOLOGY, vol. 153, no. 6, 1998, pages 1731 - 9, XP002100812
PETER J. F. SNIJDERS ET AL.: "The use of general primers in the polymerase chain reaction permits the detection of a broad spectrum of human papillomavirus genotypes", J OF GENERAL VIROLOGY, vol. 71, 1990, pages 173 - 81
See also references of EP 2455487A4
Attorney, Agent or Firm:
MI PATENT & LAW FIRM (Hongeun Bldg. 824-22,Yeoksam-dong, Gangnam-gu, Seoul 135-080, KR)
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