Title:
CHRONIC LYMPHOCYTIC LEUKEMIA MODELED IN MOUSE BY TARGETED miR-29 EXPRESSION
Document Type and Number:
WIPO Patent Application WO/2011/163116
Kind Code:
A3
Abstract:
A mouse model and uses there of for detecting, treating, characterizing, and diagnosing various diseases are described.
Inventors:
CROCE CARLO M (US)
PEKARSKY YURI (US)
PEKARSKY YURI (US)
Application Number:
PCT/US2011/041046
Publication Date:
May 03, 2012
Filing Date:
June 20, 2011
Export Citation:
Assignee:
UNIV OHIO STATE (US)
CROCE CARLO M (US)
PEKARSKY YURI (US)
CROCE CARLO M (US)
PEKARSKY YURI (US)
International Classes:
C07H21/04; G01N33/00; C40B30/06
Foreign References:
| US20090220589A1 | 2009-09-03 | |||
| US20100004322A1 | 2010-01-07 |
Other References:
SANTANAM ET AL.: "Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression.", PROC. NATL ACAD SCI. USA., vol. 107, no. 27, 21 June 2010 (2010-06-21), pages 12210 - 12215, XP002719312, DOI: doi:10.1073/pnas.1007186107
TEACHEY ET AL.: "Mammalian target of rapamycin inhibitors and their potential role in therapy in leukaemia and other haematological malignancies.", BR. J. HAEMATOL., vol. 145, no. 5, 2009, pages 569 - 580
TEACHEY ET AL.: "Mammalian target of rapamycin inhibitors and their potential role in therapy in leukaemia and other haematological malignancies.", BR. J. HAEMATOL., vol. 145, no. 5, 2009, pages 569 - 580
Attorney, Agent or Firm:
MARTINEAU, Catherine, B. (Sobanski & Todd LLC, One Maritime Plaza, US)
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