Title:
CINNAMIC ACID AMIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2014/104272
Kind Code:
A1
Abstract:
The present invention provides a cinnamic acid amide derivative having an excellent analgesic activity. The cinnamic acid amide derivative according to the present invention is a compound that exhibits an excellent analgesic activity on a nociceptive pain model animal as well as a neuropathic pain model animal, and is extremely useful as a medicine for treating various painful diseases in which acute or chronic pain or neuropathic pain is developed.
Inventors:
OOKUBO TOMOHIRO (JP)
NAKAMURA KO (JP)
NAKAZAWA YOSHITAKA (JP)
NANBA HIROYOSHI (JP)
YOSHIDA HIROYUKI (JP)
NAKAMURA KO (JP)
NAKAZAWA YOSHITAKA (JP)
NANBA HIROYOSHI (JP)
YOSHIDA HIROYUKI (JP)
Application Number:
PCT/JP2013/085041
Publication Date:
July 03, 2014
Filing Date:
December 27, 2013
Export Citation:
Assignee:
NIPPON ZOKI PHARMACEUTICAL CO (JP)
International Classes:
C07C233/22; A61K31/165; A61K31/40; A61K31/4045; A61K31/415; A61K31/4174; A61K31/4192; A61K31/4196; A61K31/42; A61K31/4402; A61K31/495; A61P25/04; C07D207/335; C07D209/14; C07D213/40; C07D231/12; C07D231/56; C07D233/64; C07D235/06; C07D249/04; C07D261/08; C07D295/12
Domestic Patent References:
| WO2008005954A2 | 2008-01-10 |
Foreign References:
| JPS5030842A | 1975-03-27 | |||
| JPS59164779A | 1984-09-17 | |||
| JP2007210974A | 2007-08-23 | |||
| JP2012510512A | 2012-05-10 | |||
| JPS5030842A | 1975-03-27 |
Other References:
TETRAHEDRON LETTERS, vol. 43, 2002, pages 3117 - 3120, XP004347873
J.MED.CHEM., vol. 47, 2004, pages 2887 - 2896, XP002388643
DATABASE REGISTRY [o] XP055289433, retrieved from STN Database accession no. 1355939- 10-4
DATABASE REGISTRY [o] XP055289448, retrieved from STN
DATABASE REGISTRY [o] XP055289451, retrieved from STN Database accession no. 1173545-05-5
DATABASE REGISTRY [o] 13 March 2011 (2011-03-13), XP055289456, retrieved from STN Database accession no. 1268315- 16-7
DATABASE REGISTRY [o] 16 April 2012 (2012-04-16), XP055289460, retrieved from STN Database accession no. 1369422-91-2
DATABASE REGISTRY [o] 24 October 2002 (2002-10-24), XP055289463, retrieved from STN Database accession no. 464909- 19-1
KIM; CHUNG, PAIN, vol. 50, 1992, pages 355 - 363
CHAPLAN ET AL., J NEUROSCI. METHOD, vol. 53, 1994, pages 55 - 63
See also references of EP 2940003A4
J.MED.CHEM., vol. 47, 2004, pages 2887 - 2896, XP002388643
DATABASE REGISTRY [o] XP055289433, retrieved from STN Database accession no. 1355939- 10-4
DATABASE REGISTRY [o] XP055289448, retrieved from STN
DATABASE REGISTRY [o] XP055289451, retrieved from STN Database accession no. 1173545-05-5
DATABASE REGISTRY [o] 13 March 2011 (2011-03-13), XP055289456, retrieved from STN Database accession no. 1268315- 16-7
DATABASE REGISTRY [o] 16 April 2012 (2012-04-16), XP055289460, retrieved from STN Database accession no. 1369422-91-2
DATABASE REGISTRY [o] 24 October 2002 (2002-10-24), XP055289463, retrieved from STN Database accession no. 464909- 19-1
KIM; CHUNG, PAIN, vol. 50, 1992, pages 355 - 363
CHAPLAN ET AL., J NEUROSCI. METHOD, vol. 53, 1994, pages 55 - 63
See also references of EP 2940003A4
Attorney, Agent or Firm:
FUJII, Ikuro (JP)
Fujii Ikuro (JP)
Fujii Ikuro (JP)
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