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Title:
CIRCULAR DICHROIC THERMAL LENS MICROSCOPE
Document Type and Number:
WIPO Patent Application WO/2006/085606
Kind Code:
A1
Abstract:
A higher-sensitivity circular dichroic thermal lens microscope capable of identifying and quantify a trace of an optically active sample. The circular dichroic thermal lens microscope which is a thermal lens microscope for detecting a substance in a sample by introducing exciting light and detecting light to an optical microscope, introducing the detecting light to a thermal lens formed by irradiating the sample with the exciting light and then measuring diffusion of the detecting light caused by the thermal lens, and which performs identification or quantification of an optical isomer by modulating exciting light by a phase modulation element.

Inventors:
YAMAUCHI MASAYO (JP)
HIHARA AKIHIDE (JP)
KITAMORI TAKEHIKO (JP)
MAWATARI KAZUMA (JP)
TOKESHI MANABU (JP)
Application Number:
PCT/JP2006/302335
Publication Date:
August 17, 2006
Filing Date:
February 10, 2006
Export Citation:
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Assignee:
KANAGAWA KAGAKU GIJUTSU AKAD (JP)
INST OF MICROCHEMICAL TECHNOLO (JP)
YAMAUCHI MASAYO (JP)
HIHARA AKIHIDE (JP)
KITAMORI TAKEHIKO (JP)
MAWATARI KAZUMA (JP)
TOKESHI MANABU (JP)
International Classes:
G01N25/16; G01N21/19; G01N21/41
Domestic Patent References:
WO2003029790A12003-04-10
Foreign References:
JP2004317646A2004-11-11
JP2003031814A2003-01-31
JP3612557B22005-01-19
Other References:
RAMIS-RAMOS G.: "Analytical characterisitcs, applications and perspectives in thermal lens spectrometry", ANALYTICA CHIMICA ACTA, vol. 283, no. 1, 15 November 1993 (1993-11-15), pages 623 - 634, XP003001964
XU M. AND TRAN C.D.: "Thermal lens-circular dichroism detector for high-performance liquid chromatography", ANALYTICAL CHEMISTRY, vol. 62, no. 22, 15 November 1990 (1990-11-15), pages 2467 - 2471, XP000165610
XU M. AND TRAN C.D.: "Thermal lens-circular dichroism spectropolarimeter", APPLIED SPECTROSCOPY, vol. 44, no. 6, July 1990 (1990-07-01), pages 962 - 966, XP000137858
TRAN C.D. AND XU M.: "Ultrasensitive thermal lens-circular dichroism spectropolarimeter for small-volume samples", REVIEW OF SCIENTIFIC INSTRUMENTS, vol. 60, no. 10, October 1989 (1989-10-01), pages 3207 - 3211, XP000071707
Attorney, Agent or Firm:
Shimizu, Hatsushi (1-1-1 Oroshi-mach, Tsuchiura-shi Ibaraki 47, JP)
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