Title:
CLASSIFICATION METHOD AND COMPUTER PROGRAM
Document Type and Number:
WIPO Patent Application WO/2024/070655
Kind Code:
A1
Abstract:
In this classification method, first, a three-dimensional embryonic image (D2) is acquired by optical coherence tomography. Then, in the three-dimensional image (D2), a blastomere area occupied by each blastomere and a fragmentation area occupied by fragmentation are extracted. Then, the volume of each of the blastomere areas and the volume of the fragmentation area are calculated. In succession, a first index value (P1) indicating a variation of the volume of the blastomere in the embryo is calculated on the basis of the volume of each of the blastomere areas. In addition, a second index value (P2) indicating a ratio of the fragmentation in the embryo is calculated on the basis of the volume of the fragmentation area. Then, the embryo is classified on the basis of the first index value (P1) and the second index value (P2). Accordingly, the embryo in a cleavage stage can be quantitatively classified on the basis of the three-dimensional image (D2).
Inventors:
HASEBE RYO (JP)
Application Number:
PCT/JP2023/033147
Publication Date:
April 04, 2024
Filing Date:
September 12, 2023
Export Citation:
Assignee:
SCREEN HOLDINGS CO LTD (JP)
International Classes:
C12N5/073; C12Q1/04; G06T7/00
Domestic Patent References:
| WO2020012616A1 | 2020-01-16 |
Foreign References:
| JP2017521067A | 2017-08-03 | |||
| JP2016509845A | 2016-04-04 | |||
| JP2019133429A | 2019-08-08 |
Attorney, Agent or Firm:
NISHIDA Takami (JP)
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