Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
CLASSIFICATION SYSTEM, METHODS AND KIT FOR CLASSIFYING. PREDICTING AND TREATING BREAST CANCER
Document Type and Number:
WIPO Patent Application WO/2014/205184
Kind Code:
A3
Abstract:
A novel classification system for breast cancer based on normal breast cell phenotypes and various expression levels of estrogen receptor (ER), androgen receptor (AR), and vitamin D receptor (VDR). The various categories of the classification system are associated with different survival rates and prognoses. The invention includes a method of classifying breast cancer comprises measuring the levels of ER, AR, and VDR in the cancerous tissue, and classifying the breast cancer into one of the above-noted categories according to expression levels. The invention includes a method of predicting the prognosis of breast cancer in a patient and a method of determining a treatment regimen for breast cancer depending on the category in which the breast cancer is classified. The invention includes a method of treating breast cancer according to the expression profile of ER, AR, and VDR detected in the cancerous tissue. Kits for detecting the same are also provided.

More Like This:
WO/2012/122571METHODS AND COMPOSITIONS FOR THE SELECTION AND OPTIMIZATION OF OLIGONUCLEOTIDE TAG SEQUENCES
WO/2014/096500METHOD FOR OBTAINING DATA USEFUL FOR THE DIFFERENTIAL DIAGNOSIS OF LUNG CANCER
WO/2001/092511PURIFICATION OF A TRIPLE HELI FORMATION WITH AN IMMOBILIZED OLIGONUCLEOTIDE
Inventors:
INCE TAN A (US)
Application Number:
PCT/US2014/043128
Publication Date:
March 12, 2015
Filing Date:
June 19, 2014
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
UNIV MIAMI (US)
International Classes:
C12Q1/68
Foreign References:
US20120157542A12012-06-21
US20060234287A12006-10-19
US20050100888A12005-05-12
Other References:
KRISHAN, AWTAR ET AL.: "Androgen and vitamin D receptor expression in archival human breast tumors.", CYTOMETRY PART B: CLINICAL CYTOMETRY, vol. 58.1, 2004, pages 53 - 60, XP055302781
See also references of EP 3011055A4
Attorney, Agent or Firm:
MALLOY, Jennie S. et al. (P.L.2800 S.W. Third Avenu, Miami FL, US)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: EXTRACTION SOLVENT CONTROL FOR REDUCING STABLE EMULSIONS

Next Patent: SLURRY HYDROCONVERSION USING ENHANCED SLURRY CATALYSTS