Title:
CLOSED-LOOP ELECTRICAL SPINAL CORD STIMULATION SYSTEM
Document Type and Number:
WIPO Patent Application WO/2021/036165
Kind Code:
A1
Abstract:
The present invention relates to a closed-loop electrical spinal cord stimulation system, comprising an epidural electrical spinal cord stimulation electrode, electrical leg stimulation electrodes, a closed-loop electrical stimulator, and a controller. The epidural electrical spinal cord stimulation electrode and the electrical leg stimulation electrodes are separately connected to the closed-loop electrical stimulator; the controller is electrically connected to the closed-loop electrical stimulator; the epidural electrical spinal cord stimulation electrode is used for epidural implantation on the spinal cord of a subject and epidural application of a first electrical stimulation to the spinal cord; each electrical leg stimulation electrode is implanted in a leg of the subject and is used for applying a second electrical stimulation to the leg; the voltage of the first electrical stimulation is 400-600 mV, and the frequency is 10-20 Hz; and the voltage of the second electrical stimulation is 1-1.5 V, and the frequency is 10-20 Hz. The closed-loop electrical spinal cord stimulation system of the present invention can send electrophysiological signals similar to the spinal cord sensory-motor neural circuit to the subject having spinal cord injury, and after closed-loop electrical stimulation, the neural circuit can be activated and reshaped, thereby promoting the recovery of the motor function of lower limbs of the subject.
Inventors:
LIU YAOBO (CN)
YANG DAN (CN)
YANG WEI (CN)
ZHOU KAI (CN)
YANG DAN (CN)
YANG WEI (CN)
ZHOU KAI (CN)
Application Number:
PCT/CN2020/071041
Publication Date:
March 04, 2021
Filing Date:
January 09, 2020
Export Citation:
Assignee:
UNIV SOOCHOW (CN)
International Classes:
A61N1/05; A61B5/00; A61N1/36
Foreign References:
| CN110404164A | 2019-11-05 | |||
| CN108744270A | 2018-11-06 | |||
| CN101496748A | 2009-08-05 | |||
| CN209137753U | 2019-07-23 | |||
| CN208877713U | 2019-05-21 |
Attorney, Agent or Firm:
CENTRAL SOUTH WELL INTELLECTUAL PROPERTY OFFICE (CN)
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