Title:
COGNITIVE FUNCTION IMPROVING AGENT
Document Type and Number:
WIPO Patent Application WO/2018/124010
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a cognitive function improving agent that effectively improves cognitive functions such as memory and learning, and a method for evaluating or selecting said cognitive function improving agent. A cognitive function improving agent that comprises a GIP function inhibitor as an active component is provided.
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Inventors:
OKAHARA FUMIAKI (JP)
KOGA YOSHITAKA (JP)
MORI TAKUYA (JP)
KOGA YOSHITAKA (JP)
MORI TAKUYA (JP)
Application Number:
PCT/JP2017/046525
Publication Date:
July 05, 2018
Filing Date:
December 26, 2017
Export Citation:
Assignee:
KAO CORP (JP)
International Classes:
A61K45/00; A61K31/16; A61K31/166; A61K31/20; A61K31/22; A61K31/23; A61K31/231; A61K31/404; A61K31/519; A61K31/683; A61K31/685; A61K31/717; A61K31/718; A61K31/722; A61K31/734; A61K31/785; A61K36/73; A61K36/899; A61K39/395; A61P25/28; C07K16/26; G01N33/15; G01N33/50
Domestic Patent References:
WO2016104439A1 | 2016-06-30 | |||
WO2003097031A1 | 2003-11-27 | |||
WO2016104439A1 | 2016-06-30 | |||
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Other References:
THANGTHAENG N. ET AL.: "Daily supplementation with mushroom (Agaricus bisporus) improves balance and working memory in aged rats", NUTRITION RESEARCH, vol. 35, no. 12, 2015, pages 1079 - 1084, XP029338471, ISSN: 0271-0166
MAHMOUD MG ET AL.: "Therapeutic potential and structural elucidation of a water-soluble polysaccharide of a wild edible mushroom Agaricus bisporus against neurodegenerative disease, Alzheimer", WORLD JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 2, no. 10, 2014, pages 1136 - 1145, XP055517968, ISSN: 2321-3310
BENNETT L. ET AL.: "Vitamin D2-enriched button mushroom(Agaricus bisporus) improves memory in both wild type and APPswe/PS1dE9 transgenic mice", PLOS ONE, vol. 8, no. 10, October 2013 (2013-10-01), pages e76362, XP055517970, ISSN: 1932-6203
FAIVRE E. ET AL.: "Effects of acute and chronic administration of GIP analogues on cognition, synaptic plasticity and neurogenesis in mice", EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 674, no. 2, 12 November 2012 (2012-11-12), pages 294 - 306, XP028434557, ISSN: 0014-2999
RAHMAN MA. ET AL.: "Interpretation of mushroom as a common therapeutic agent for Alzheimer's disease and cardiovascular diseases", CRC CRITICAL REVIEWS IN BIOTECHNOLOGY, vol. 36, no. 6, 30 October 2015 (2015-10-30), pages 1131 - 1142, XP055517973, ISSN: 0738-8551
MIYAWAKI K. ET AL., NAT. MED., vol. 8, no. 7, 2002, pages 738 - 42
MACCFFERTY, J. ET AL., NATURE, vol. 348, 1990, pages 552 - 554
TIM CLACKSON ET AL., NATURE, vol. 352, 1991, pages 642 - 628
KOHLER ET AL., NATURE, vol. 256, 1975, pages 495 - 497
See also references of EP 3569248A4
MAHMOUD MG ET AL.: "Therapeutic potential and structural elucidation of a water-soluble polysaccharide of a wild edible mushroom Agaricus bisporus against neurodegenerative disease, Alzheimer", WORLD JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 2, no. 10, 2014, pages 1136 - 1145, XP055517968, ISSN: 2321-3310
BENNETT L. ET AL.: "Vitamin D2-enriched button mushroom(Agaricus bisporus) improves memory in both wild type and APPswe/PS1dE9 transgenic mice", PLOS ONE, vol. 8, no. 10, October 2013 (2013-10-01), pages e76362, XP055517970, ISSN: 1932-6203
FAIVRE E. ET AL.: "Effects of acute and chronic administration of GIP analogues on cognition, synaptic plasticity and neurogenesis in mice", EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 674, no. 2, 12 November 2012 (2012-11-12), pages 294 - 306, XP028434557, ISSN: 0014-2999
RAHMAN MA. ET AL.: "Interpretation of mushroom as a common therapeutic agent for Alzheimer's disease and cardiovascular diseases", CRC CRITICAL REVIEWS IN BIOTECHNOLOGY, vol. 36, no. 6, 30 October 2015 (2015-10-30), pages 1131 - 1142, XP055517973, ISSN: 0738-8551
MIYAWAKI K. ET AL., NAT. MED., vol. 8, no. 7, 2002, pages 738 - 42
MACCFFERTY, J. ET AL., NATURE, vol. 348, 1990, pages 552 - 554
TIM CLACKSON ET AL., NATURE, vol. 352, 1991, pages 642 - 628
KOHLER ET AL., NATURE, vol. 256, 1975, pages 495 - 497
See also references of EP 3569248A4
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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