Title:
COLOR SPACE ANALYSIS IN BIOCHEMICAL AND IMMUNOLOGICAL ASSAYS
Document Type and Number:
WIPO Patent Application WO2001011359
Kind Code:
A3
Abstract:
A process is provided for analyzing a specimen of biological material in any of a number of biochemical or immunological tests for an analyte which involves subjecting the specimen to treatment which develops a color correlating to the amount of analyte in the specimen. According to the invention at least one defined color characteristic selected from hue angle, chroma, saturation and lightness of the developed color is measured and the results of that measurement analyzed to determine the presence or concentration of the analyte in the specimen. Particular applications are to the detection of cancerous or pre-cancerous abnormalities from the analysis of lung mucus, throat mucus, cervical mucus or seminal fluid.
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Inventors:
EVELEGH MICHAEL J (CA)
Application Number:
PCT/CA2000/000918
Publication Date:
December 06, 2001
Filing Date:
August 04, 2000
Export Citation:
Assignee:
IMI INTERNAT MEDICAL INNOVATIO (CA)
EVELEGH MICHAEL J (CA)
EVELEGH MICHAEL J (CA)
International Classes:
C12Q1/26; G01J3/46; C12Q1/28; C12Q1/54; C12Q1/60; G01N21/27; G01N21/78; G01N33/483; G01N33/52; G01N33/574; G01N33/68; G01N33/92; (IPC1-7): G01N33/574
Domestic Patent References:
| WO1990000251A1 | 1990-01-11 | |||
| WO1996040924A2 | 1996-12-19 | |||
| WO1990011526A1 | 1990-10-04 | |||
| WO1995014927A1 | 1995-06-01 | |||
| WO1996008710A1 | 1996-03-21 | |||
| WO1998037424A1 | 1998-08-27 |
Foreign References:
| EP0893690A1 | 1999-01-27 | |||
| EP0110173A1 | 1984-06-13 | |||
| US5587295A | 1996-12-24 | |||
| DE4331010A1 | 1995-03-16 |
Other References:
GOTO M ET AL: "Chromaticity analysis of Immunostained Tumor Specimens", PATHOLOGY RESEARCH AND PRACTICE, vol. 188, no. 4,5, June 1992 (1992-06-01), pages 433 - 437, XP000972430
SINCOCK ANDREW: "Computerised laser analysis of breast sections and cervical smears by transnuclear scanning.", MEDICAL SCIENCE RESEARCH, vol. 24, no. 3, 1996, pages 165 - 166, XP000972530, ISSN: 0269-8951
GALBRAITH W ET AL: "COLORIMETRY FOR THE STAIN TECHNOLOGIST 4. ANALYSIS OF THE COMPONENTS OF COLOR DIFFERENCE", STAIN TECHNOLOGY, vol. 60, no. 4, 1985, pages 239 - 246, XP000972409, ISSN: 0038-9153
EVELEGH M J ET AL: "Use of skin cholesterol to monitor response to cholesterol-lowering therapy.", CLINICAL CHEMISTRY, vol. 45, no. 6 PART 2, June 1999 (1999-06-01), 51st Annual Meeting of the American Association of Clinical Chemistry;New Orleans, Louisiana, USA; July 25-29, 1999, pages A29, XP002160743, ISSN: 0009-9147
SINCOCK ANDREW: "Computerised laser analysis of breast sections and cervical smears by transnuclear scanning.", MEDICAL SCIENCE RESEARCH, vol. 24, no. 3, 1996, pages 165 - 166, XP000972530, ISSN: 0269-8951
GALBRAITH W ET AL: "COLORIMETRY FOR THE STAIN TECHNOLOGIST 4. ANALYSIS OF THE COMPONENTS OF COLOR DIFFERENCE", STAIN TECHNOLOGY, vol. 60, no. 4, 1985, pages 239 - 246, XP000972409, ISSN: 0038-9153
EVELEGH M J ET AL: "Use of skin cholesterol to monitor response to cholesterol-lowering therapy.", CLINICAL CHEMISTRY, vol. 45, no. 6 PART 2, June 1999 (1999-06-01), 51st Annual Meeting of the American Association of Clinical Chemistry;New Orleans, Louisiana, USA; July 25-29, 1999, pages A29, XP002160743, ISSN: 0009-9147
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