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Title:
COMBINATION OF AKR1C3 ACTIVATED ANTICANCER PRODRUG COMPOUND AND ANALGESIC DRUG FOR TREATING CANCER PATIENTS ACCOMPANIED BY PAIN
Document Type and Number:
WIPO Patent Application WO/2024/078568
Kind Code:
A1
Abstract:
Provided in the present invention are a treatment method for treating cancer patients accompanied by pain by using a combination of an AKR1C3 activated anticancer prodrug compound and an analgesic drug, a pharmaceutical use, a drug combination and a pharmaceutical preparation thereof. A reasonable selection scheme is provided for the clinical treatment of cancers, and in particular, the effects of simultaneously treating cancers and relieving pain can be achieved by means of the combination of AST-3424 and a non-steroidal analgesic drug.

Inventors:
DUAN JIANXIN (CN)
XIE YANBIN (CN)
MENG FANYING (US)
HAO JING (CN)
QI TIANYANG (CN)
LIU XING (CN)
LI BING (CN)
Application Number:
PCT/CN2023/124204
Publication Date:
April 18, 2024
Filing Date:
October 12, 2023
Export Citation:
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Assignee:
ASCENTAWITS PHARMACEUTICALS LTD (CN)
International Classes:
A61K45/06; A61K31/664; A61P29/00; A61P35/00
Attorney, Agent or Firm:
SHANGHAI DANRONG & ZONGDE INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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