Title:
COMBINATION OF DRUGS WITH ANTISEPTIC EFFECT
Document Type and Number:
WIPO Patent Application WO/2016/136642
Kind Code:
A1
Abstract:
Provided is a drug composition containing dorzolamide or a salt thereof and timolol or a salt thereof, said novel drug composition being capable of exhibiting an adequate antiseptic effect, even if a container is opened and closed repeatedly. The pharmaceutical composition of the present invention, containing dorzolamide or a salt thereof, and timolol or a salt thereof, does not contain benzalkonium chlorides, and is stored in a reusable container. The present invention further pertains to a method for improving antiseptic effect by further including dorzolamide or a salt thereof in a drug composition kept in a multi-dose vial, said drug composition containing timolol or a salt thereof and not containing benzalkonium chlorides.
Inventors:
MORIMOTO TAKASHI (JP)
MATSUMOTO NAOKI (JP)
OKI KENJI (JP)
ASADA HIROYUKI (JP)
TSUBOI TAKASHI (JP)
MATSUMOTO NAOKI (JP)
OKI KENJI (JP)
ASADA HIROYUKI (JP)
TSUBOI TAKASHI (JP)
Application Number:
PCT/JP2016/054976
Publication Date:
September 01, 2016
Filing Date:
February 22, 2016
Export Citation:
Assignee:
SANTEN PHARMACEUTICAL CO LTD (JP)
International Classes:
A61K31/5377; A61K31/382; A61K47/04; A61K47/12; A61K47/30; A61P27/06
Foreign References:
| JPH05117167A | 1993-05-14 | |||
| US20100210720A1 | 2010-08-19 | |||
| JP2010537791A | 2010-12-09 |
Other References:
BAROT, M. ET AL.: "Trends in Ophthalmic Preservatives : A Review", DRUG DELIVERY TECHNOLOGY, vol. 10, no. 6, 2010, pages 46 - 49, XP055182914
Attorney, Agent or Firm:
SHOBAYASHI, Masayuki et al. (JP)
Right wood Masayuki (JP)
Right wood Masayuki (JP)
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