COMBINATION OF TRIMEBUTINE WITH AN OPIOID ANALGESIC

Title:

COMBINATION OF TRIMEBUTINE WITH AN OPIOID ANALGESIC

Document Type and Number:

WIPO Patent Application WO2001047508

Kind Code:

A3

Abstract:

The invention provides a combination of of trimebutine [2-dimethylamino-2-phenylbutyl-3, 4, 5- trimethoxy-benzoate hydrogen maleate] or its corresponding stereoisomers with an opioid analgesic for the preparation of a medicament to prevent and/or treat pain or nociception.

Inventors:

HAMON JACQUES (FR)
ROMAN FRANCOIS (FR)

Application Number:

PCT/EP2000/013183

Publication Date:

December 13, 2001

Filing Date:

December 19, 2000

Export Citation:

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Assignee:

WARNER LAMBERT CO (US)
HAMON JACQUES (FR)
ROMAN FRANCOIS (FR)

International Classes:

A61K31/135; A61K31/222; A61K31/24; A61K31/439; A61K45/00; A61K31/445; A61K31/451; A61K31/485; A61P23/00; A61P23/02; A61P25/04; A61P43/00; (IPC1-7): A61P43/00; A61K31/485

Other References:

ROMAN F J ET AL: "PHARMACOLOGICAL PROPERTIES OF TRIMEBUTINE AND N-MONODESMETHYLTRIMEBUTINE", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS,AMERICAN SOCIETY FOR PHARMACOLOGY AND,US, vol. 289, no. 3, 1999, pages 1391 - 1397, XP000985364, ISSN: 0022-3565

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