Title:
COMBINATIONS COMPRISING A SELECTIVE CYCLOOXYGENASE-2 INHIBITOR
Document Type and Number:
WIPO Patent Application WO2003035047
Kind Code:
A3
Abstract:
A combination therapy for treating patients suffering from pre-malignant colon lesions (e.g. polyps) and colon cancer, as well as other malignancies, is disclosed. The patient is treated concurrently with a cycloocygenase-2 inhibitor and at least one compound selected from the group consisting of a microtubule interfering agent, an epithelial growth factor receptor tyrosine protein kinase inhibitor and a vascular endothelial growth factor receptor tyrosine kinase inhibitor.
Inventors:
CHEN YING-NAN PAN (US)
LASSOTA PETER (US)
WOOD ALEXANDER WALLACE (US)
LASSOTA PETER (US)
WOOD ALEXANDER WALLACE (US)
Application Number:
PCT/EP2002/011924
Publication Date:
October 23, 2003
Filing Date:
October 24, 2002
Export Citation:
Assignee:
NOVARTIS AG (CH)
NOVARTIS PHARMA GMBH (AT)
CHEN YING-NAN PAN (US)
LASSOTA PETER (US)
WOOD ALEXANDER WALLACE (US)
NOVARTIS PHARMA GMBH (AT)
CHEN YING-NAN PAN (US)
LASSOTA PETER (US)
WOOD ALEXANDER WALLACE (US)
International Classes:
A61K31/165; A61K31/195; A61K31/337; A61K31/365; A61K31/366; A61K31/426; A61K31/475; A61K31/502; A61K31/196; A61K31/5025; A61K45/06; A61P35/00; A61P43/00; (IPC1-7): A61K31/196; A61P35/00; A61K31/502; A61K31/195; A61K45/06; A61K31/50
Domestic Patent References:
| WO2001064669A1 | 2001-09-07 | |||
| WO2001040216A1 | 2001-06-07 | |||
| WO2001062252A1 | 2001-08-30 | |||
| WO1998035958A1 | 1998-08-20 | |||
| WO1999011605A1 | 1999-03-11 | |||
| WO2001060365A1 | 2001-08-23 | |||
| WO2001012227A1 | 2001-02-22 | |||
| WO2001047507A2 | 2001-07-05 |
Foreign References:
| EP0927555A1 | 1999-07-07 | |||
| US6034256A | 2000-03-07 |
Other References:
See also references of EP 1441714A2
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