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Title:
COMBINATORIAL SYNTHESIS ON SUPPORT
Document Type and Number:
WIPO Patent Application WO2005016514
Kind Code:
A3
Abstract:
Methods are disclosed for providing a library of composite or novel composition samples on a support. The method involves depositing one or more components as concentration gradients on the surface of the support. The concentration gradients are placed on the support in the form of superimposed triangles which allow ready formation of composite or composition samples containing three or more components. The samples can be removed from the support by drilling out portions of the coated support so as to yield individual tablets containing the support with one or more component layers thereon. By using this method, a vast number of samples can be made.

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Inventors:
CASTELLANO CHRISTOPHER R
MOINI AHMAD
KOERMER GERALD
Application Number:
PCT/US2004/020668
Publication Date:
May 12, 2005
Filing Date:
June 25, 2004
Export Citation:
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Assignee:
ENGELHARD CORP (US)
International Classes:
A61K31/7024; C07H13/12; A61K31/7052; A61K31/7056; A61K31/706; A61P3/10; A61P11/06; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P37/06; A61P41/00; B01J19/00; C07H9/04; C07H19/02; C07H19/04; C40B30/08; C40B40/18; C40B60/14; (IPC1-7): B01J19/00
Domestic Patent References:
WO2000017413A22000-03-30
WO2002024321A12002-03-28
WO1998047613A11998-10-29
Foreign References:
US6364956B12002-04-02
US20030073246A12003-04-17
Other References:
DANIELSON E ET AL: "A COMBINATORIAL APPROACH TO THE DISCOVERY AND OPTIMIZATION OF LUMINESCENT MATERIALS", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 389, no. 6654, 30 October 1997 (1997-10-30), pages 944 - 948, XP000867785, ISSN: 0028-0836
SENKAN S M ET AL: "DISCOVERY AND OPTIMIZATION OF HETEROGENEOUS CATALYSTS BY USING COMBINATORIAL CHEMISTRY", ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, VERLAG CHEMIE. WEINHEIM, DE, vol. 38, no. 6, March 1999 (1999-03-01), pages 791 - 795, XP001065267, ISSN: 0570-0833
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