Title:
COMBINED PHARMACEUTICAL COMPOSITION AS ANTIFUNGAL AGENT
Document Type and Number:
WIPO Patent Application WO/2012/060448
Kind Code:
A1
Abstract:
The purpose of the invention is to provide a pharmaceutical composition having excellent antifungal activity. The invention provides a pharmaceutical composition comprising 3-(3-(4-(pyridin-2-yloxymethyl)-benzyl)-isoxazol-5-yl)-pyridin-2-ylamine or 2-amino-1-((phosphonoxy)methyl)-3-(3-((4-((2-pyridinyloxy)methyl)phenyl)methyl)-5-isoxazolyl)-pyridinium or a salt thereof and an antifungal agent in combination.
Inventors:
WATANABE NAOAKI (JP)
HATA KATSURA (JP)
MIYAZAKI MAMIKO (JP)
HORII TAKAAKI (JP)
HATA KATSURA (JP)
MIYAZAKI MAMIKO (JP)
HORII TAKAAKI (JP)
Application Number:
PCT/JP2011/075481
Publication Date:
May 10, 2012
Filing Date:
November 04, 2011
Export Citation:
Assignee:
EISAI R&D MAN CO LTD (JP)
WATANABE NAOAKI (JP)
HATA KATSURA (JP)
MIYAZAKI MAMIKO (JP)
HORII TAKAAKI (JP)
WATANABE NAOAKI (JP)
HATA KATSURA (JP)
MIYAZAKI MAMIKO (JP)
HORII TAKAAKI (JP)
International Classes:
A61K31/4174; A61K31/444; A61K31/4196; A61K31/427; A61K31/496; A61K31/505; A61K31/506; A61K31/7048; A61K38/00; A61K45/00; A61P31/10; A61P43/00
Domestic Patent References:
| WO2007052615A1 | 2007-05-10 | |||
| WO2009084621A1 | 2009-07-09 | |||
| WO2008044562A1 | 2008-04-17 | |||
| WO1998010782A1 | 1998-03-19 | |||
| WO2008044562A1 | 2008-04-17 | |||
| WO2009144473A1 | 2009-12-03 | |||
| WO2007052615A1 | 2007-05-10 | |||
| WO2009084621A1 | 2009-07-09 | |||
| WO2006003881A1 | 2006-01-12 | |||
| WO2009130481A1 | 2009-10-29 | |||
| WO2001052852A1 | 2001-07-26 |
Foreign References:
| JPH0820578A | 1996-01-23 |
Other References:
YOSHIHITO NIKI ET AL.: "Combination effect of micafungin with amphotericin B, itraconazole and fluconazole", JAPANESE JOURNAL OF CHEMOTHERAPY, vol. 50, no. SUP.1, 2002, pages 58 - 67, XP003002829
"Shinzaisei Shinkinsho No Shindan Chiryo Gaidorain", 2003, ISHIYAKU PUBLISHERS, INC
ANTIMICROB. AGENTS CHEMOTHER., vol. 52, 2008, pages 1318 - 1324
"Shinzaisei Shinkinsho No Shindan Chiryo Gaidorain", 2003, ISHIYAKU PUBLISHERS, INC
ANTIMICROB. AGENTS CHEMOTHER., vol. 52, 2008, pages 1318 - 1324
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
Yoshiyuki Inaba (JP)
Yoshiyuki Inaba (JP)
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