COMBINED PHARMACEUTICAL COMPOSITION FOR PREVENTING CARDIOVASCULAR DISEASES COMPLICATED BY HYPERTENSION AND APPLICATION THEREOF

Title:

COMBINED PHARMACEUTICAL COMPOSITION FOR PREVENTING CARDIOVASCULAR DISEASES COMPLICATED BY HYPERTENSION AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2023/272794

Kind Code:

A1

Abstract:

A combined pharmaceutical composition for preventing cardiovascular diseases complicated by hypertension, comprising a homocysteine reducing drug and a platelet reducing drug. The homocysteine reducing drug is folic acid, and the platelet reducing drug is aspirin or clopidogrel. The combined pharmaceutical composition can be used not only for blood pressure management of hypertensive patients but also for prevention of cardiovascular events of the hypertensive patients.

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Inventors:

PENG HAO (CN)
LI JING (CN)
CHEN LINAN (CN)
LU YING (CN)

Application Number:

PCT/CN2021/106674

Publication Date:

January 05, 2023

Filing Date:

July 16, 2021

Export Citation:

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Assignee:

UNIV SOOCHOW (CN)

International Classes:

A61K31/4365; A61K45/06; A61K31/4415; A61K31/519; A61K31/616; A61K31/714; A61P9/00; A61P9/04; A61P9/10; A61P9/12

Domestic Patent References:

WO2007091253A2

2007-08-16

Foreign References:

CN101897709A

2010-12-01

Other References:

XIE FENG,LI JING,YANG HUI-MIN,YU MU-SHENG,ZHENG WEN-CHU,YANG GUO-ZHANG: "Epidemiological Survey of H-type Hypertension and Intervention Study of Low Dose of Folic Acid", CHINESE JOURNAL OF ETHNOMEDICINE AND ETHNOPHARMACY, vol. 22, no. 12, 30 June 2013 (2013-06-30), pages 54 - 55, XP093020237, ISSN: 1007-8517
WU XUEFENG;LI AIGUO;LIN WEIDONG: "Effects of Aspirin Combined with Folic Acid on Serum Hcy, CRP, IL-6 and TNF-α Levels in Elderly Hypertensive Patients", JOURNAL OF PHARMACEUTICAL RESEARCH, vol. 36, no. 11, 15 November 2017 (2017-11-15), pages 673 - 675, XP093020238, ISSN: 2095-5375, DOI: 10.13506/j.cnki.jpr.2017.11.015

Attorney, Agent or Firm:

CENTRAL SOUTH WELL INTELLECTUAL PROPERTY OFFICE (CN)

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