Title:
COMBRETASTATIN ANALOGS
Document Type and Number:
WIPO Patent Application WO/2014/172363
Kind Code:
A3
Abstract:
The present invention relates novel heterocyclic analogs of combretastatin, their synthesis, and their use as anti-cancer compounds. In particular, compounds of Formula (I), Formula (II), and Formula (V) are provided.
Inventors:
PENTHALA NARSIMHA REDDY (US)
CROOKS PETER (US)
SONAR VIJAYAKUMAR (US)
CROOKS PETER (US)
SONAR VIJAYAKUMAR (US)
Application Number:
PCT/US2014/034185
Publication Date:
December 31, 2014
Filing Date:
April 15, 2014
Export Citation:
Assignee:
UNIV ARKANSAS (US)
PENTHALA NARSIMHA REDDY (US)
CROOKS PETER (US)
SONAR VIJAYAKUMAR (US)
PENTHALA NARSIMHA REDDY (US)
CROOKS PETER (US)
SONAR VIJAYAKUMAR (US)
International Classes:
C07D307/80; A61K31/47
Foreign References:
| US20090253656A1 | 2009-10-08 |
Other References:
PENTHALA ET AL.: "Synthesis and In Vitro Screening of Novel Heterocyclic Compounds as Potential Breast Cancer Agents", BREAST CANCER - CURRENT AND ALTERNATIVE THERAPEUTIC MODALITIES, 2011, pages 283 - 294, XP055293863, ISBN: 978-953-307-776-5, Retrieved from the Internet
PENTHALA ET AL.: "Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents", MEDCHEMCOMM., vol. 4, no. 7, 1 July 2013 (2013-07-01), pages 1073 - 1078, XP055293864
See also references of EP 2986596A4
PENTHALA ET AL.: "Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents", MEDCHEMCOMM., vol. 4, no. 7, 1 July 2013 (2013-07-01), pages 1073 - 1078, XP055293864
See also references of EP 2986596A4
Attorney, Agent or Firm:
BARRON, Briana et al. (105 West Vandalia Street,Suite 40, Edwardsville Illinois, US)
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