Title:
COMPARATIVE ANALYSIS METHOD FOR DATA OBTAINED THROUGH LC-MALDI
Document Type and Number:
WIPO Patent Application WO/2012/029900
Kind Code:
A1
Abstract:
[Problem] To provide a method for determining the homology of precursor ions obtained by subjecting sample fractions separated by liquid chromatography (LC) to spotting at a prescribed position in a prescribed order on a sample plate, then subjecting these fractions to a tandem mass spectrometer (MS/MS) provided with an ionization unit using the matrix-assisted laser desorption/ionization (MALDI) technique. [Solution] A method including a step for determining precursor ions are homologous in the case that: (1) in relation to the position on a sample plate obtained by a precursor ion derived from a first sample, the position on a sample plate obtained by a precursor ion derived from a second sample satisfies a prescribed relationship; and (2) a comparison of the product ion groups of both precursor ions reveals that both precursor ions are homologous.
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Inventors:
YOSHIDA MASAKI (JP)
KUROIWA TSUNEYOSHI (JP)
YOSHIDA YAMATO (JP)
KUROIWA TSUNEYOSHI (JP)
YOSHIDA YAMATO (JP)
Application Number:
PCT/JP2011/069885
Publication Date:
March 08, 2012
Filing Date:
September 01, 2011
Export Citation:
Assignee:
RIKKYO GAKUIN (JP)
YOSHIDA MASAKI (JP)
KUROIWA TSUNEYOSHI (JP)
YOSHIDA YAMATO (JP)
YOSHIDA MASAKI (JP)
KUROIWA TSUNEYOSHI (JP)
YOSHIDA YAMATO (JP)
International Classes:
G01N27/62; G01N27/64
Foreign References:
| JP2008249440A | 2008-10-16 | |||
| JP2009156722A | 2009-07-16 | |||
| JP2006525520A | 2006-11-09 | |||
| JP2004529325A | 2004-09-24 |
Attorney, Agent or Firm:
IDE Masatake et al. (JP)
Masatake Ide (JP)
Masatake Ide (JP)
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Claims: