Title:
COMPLEX OF COMPOUND HAVING CHALCONE SKELETON
Document Type and Number:
WIPO Patent Application WO/1993/006075
Kind Code:
A1
Abstract:
A solid preparation exhibiting a good absorbability of 4-t-butyl-2'-carboxymethoxy-4'-(3-methyl-2-butenyloxy)chalcone and 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)chalcone and available for treating gastric ulcer and gastritis as a protective factor. A complex having an improved bioavailability and an excellent antiulcer activity is provided by forming a clathrate complex between the chalcone and cyclodextrin.
Inventors:
ITO SHUSEI (JP)
ITAI SHIGERU (JP)
UMEKI NOBUO (JP)
ITAI SHIGERU (JP)
UMEKI NOBUO (JP)
Application Number:
PCT/JP1992/001199
Publication Date:
April 01, 1993
Filing Date:
September 21, 1992
Export Citation:
Assignee:
TAISHO PHARMACEUTICAL CO LTD (JP)
International Classes:
A61K31/22; A61K47/48; C07C59/90; C08B37/00; (IPC1-7): A61K31/12; A61K31/19; A61K31/215; A61K47/40; C07C49/76; C07C69/92; C08B37/16
Foreign References:
| JPH01249763A | 1989-10-05 |
Other References:
See also references of EP 0604653A4
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