COMPLEX COMPOUND AND MRI PROBE MADE OF SAME - JAPAN SCIENCE & TECH AGENCY

Title:

COMPLEX COMPOUND AND MRI PROBE MADE OF SAME

Document Type and Number:

WIPO Patent Application WO/2006/095771

Kind Code:

A1

Abstract:

Disclosed is a novel gadolinium complex compound exhibiting responsiveness to compounds and ions other than zinc ion. Also disclosed is an MRI probe made of such a gadolinium complex compound. Specifically disclosed is a gadolinium complex compound having a specific structure represented by the structural formula shown below. This gadolinium complex compound is responsive to potassium ion, calcium ion, glucose and the like. Consequently, by using this gadolinium complex compound as an MRI probe, these ions or compounds within a living body can be sensed or the concentration distribution thereof can be obtained.

Inventors:

SUZUKI KOJI (JP)
HIFUMI HIROKI (JP)
TANIMOTO AKIHIRO (JP)
MAKINO MEGUMI (JP)

Application Number:

PCT/JP2006/304474

Publication Date:

September 14, 2006

Filing Date:

March 08, 2006

Export Citation:

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Assignee:

JAPAN SCIENCE & TECH AGENCY (JP)
SUZUKI KOJI (JP)
HIFUMI HIROKI (JP)
TANIMOTO AKIHIRO (JP)
MAKINO MEGUMI (JP)

International Classes:

C07C237/04; A61B5/055; A61K49/00; C07D257/02; C07D323/00; C07F5/00; C07F5/02

Foreign References:

JP2001523650A

2001-11-27

Other References: