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Title:
COMPLEX DISINTEGRANT SYSTEM FOR ORAL SOLID PREPARATION AND ORAL SOLID PREPARATION COMPRISING SAID COMPLEX DISINTEGRANT SYSTEM
Document Type and Number:
WIPO Patent Application WO/2018/010543
Kind Code:
A1
Abstract:
A complex disintegrant composition for oral solid preparation, comprising a disintegrant and a disintegrating aid, the disintegrant being a hygroscopic expansion type disintegrant, the disintegrating aid being a soluble small molecule substance or a gas-producing type salt. An oral solid preparation, comprising an active ingredient, said complex disintegrant composition, an excipient and a lubricant.

Inventors:
WAN YAOWEN (CN)
CHEN YONGKAI (CN)
ZENG XIAN (CN)
WANG CHAODONG (CN)
FENG WEI (CN)
Application Number:
PCT/CN2017/090374
Publication Date:
January 18, 2018
Filing Date:
June 27, 2017
Export Citation:
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Assignee:
WUHAN LL SCIENCE AND TECH DEVELOPMENT CO LTD (CN)
WUHAN QR PHARMACEUTICALS CO LTD (CN)
International Classes:
A61K9/20; A61K31/4245; A61K31/497; A61K47/02; A61K47/26; A61K47/32; A61K47/36; A61K47/38; A61P3/10; A61P13/12
Foreign References:
CN105153141A2015-12-16
Other References:
HONG, QIUBING ET AL.: "Preparation for Zinc Gluconate Effervescent Tablets and its Quality Control", CLINICAL JOURNAL OF MEDICAL OFFICER = LIN CHUANG JUN YI ZA ZHI, vol. 41, no. 2, 15 February 2016 (2016-02-15), CN, pages 192 - 193,202, XP009513274, ISSN: 1671-3826
HONG, QIUBING ET AL.: "Preparation for Zinc Gluconate Effervescent Tablets and its Quality Control", CLINICAL JOURNAL OF MEDICAL OFFICER = LIN CHUANG JUN YI ZA ZHI, vol. 41, no. 2, 15 February 2013 (2013-02-15), CN, pages 192 - 193,202, XP009513274
Attorney, Agent or Firm:
WUHAN ORIGINTELLIGENCE IP LAW FIRM (CN)
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