Title:
COMPOSITE OF ANGIOTENSIN II RECEPTOR ANTAGONIST AND NEP INHIBITOR AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2021/093697
Kind Code:
A1
Abstract:
Provided is a series of supramolecular complexes (composites) having a dual function. The supramolecular complexes (composites) comprise a compound having an angiotensin II receptor (AT1) blocking function, a neprilysin inhibitor (NEPi) and a pharmaceutically acceptable cation.
Inventors:
LI SONG (CN)
XU WENJIE (CN)
CHENG CHONG (CN)
SUN JINGCHAO (CN)
HUA HUAIJIE (CN)
XU WENJIE (CN)
CHENG CHONG (CN)
SUN JINGCHAO (CN)
HUA HUAIJIE (CN)
Application Number:
PCT/CN2020/127415
Publication Date:
May 20, 2021
Filing Date:
November 09, 2020
Export Citation:
Assignee:
SHENZHEN SALUBRIS PHARM CO LTD (CN)
International Classes:
C07D403/10; A61K31/216; A61K31/41; A61P9/00; C07C231/12; C07C233/47
Domestic Patent References:
| WO2017125031A1 | 2017-07-27 |
Foreign References:
| CN105982891A | 2016-10-05 | |||
| CN106146472A | 2016-11-23 | |||
| CN105963296A | 2016-09-28 |
Other References:
ANONYMITY: "European Medicines Agency: Assessment report Entresto International non- proprietary", ASSESSMENT REPORT, 24 September 2015 (2015-09-24), pages 1 - 115, XP055609648
Download PDF: