Title:
COMPOSITE ZIRCONIA-CALCIUM PHOSPHATE CERAMIC FOR DENTAL IMPLANTS
Document Type and Number:
WIPO Patent Application WO/2013/004361
Kind Code:
A3
Abstract:
A bioactive ceramic nanocomposite is described as follows. The composite material comprises a ceramic nanocomposite including a plurality of first grains which include calcium phosphate. The average grain size is one micron or less. The calcium phosphate is present in the nanocomposite material in the range of 10% by weight to 70% by weight based on the total weight of the nanocomposite material. A plurality of second grains is rapid sintered to the calcium phosphate-containing grains by using a dynamic sintering technique, such as spark plasma sintering (SPS). The second type of grains may be selected from the group consisting of zirconia and alumina and also have an average grain size of one micron or less. Preferably the zirconia contains 2-10 wt% yttria.
Inventors:
GRUENER DANIEL (DE)
FAELDT JENNY (SE)
ADOLFSSON ERIK (SE)
SHEN ZHIJAN (SE)
FAELDT JENNY (SE)
ADOLFSSON ERIK (SE)
SHEN ZHIJAN (SE)
Application Number:
PCT/EP2012/002721
Publication Date:
August 29, 2013
Filing Date:
June 28, 2012
Export Citation:
Assignee:
NOBEL BIOCARE SERVICES AG (CH)
GRUENER DANIEL (DE)
FAELDT JENNY (SE)
ADOLFSSON ERIK (SE)
SHEN ZHIJAN (SE)
GRUENER DANIEL (DE)
FAELDT JENNY (SE)
ADOLFSSON ERIK (SE)
SHEN ZHIJAN (SE)
International Classes:
C04B35/117; A61C8/00; A61K6/02; A61K6/838; C04B35/447; C04B35/488; C04B35/645
Foreign References:
| US6013591A | 2000-01-11 |
Other References:
GUO ET AL.: "Laminated and functionally graded hydroxyapatite/yttria stabilized tetragonal zirconia composites fabricated by spark plasma sintering", BIOMATERIALS, vol. 24, 2003, pages 667 - 675, XP004393192
GAO ET AL.: "Fabrication of HAp-Zr02 (3Y) nano-composite by SPS", BIOMATERIALS, vol. 24, 2003, pages 937 - 940, XP004399586
ERIK ADOLFSSON ET AL: "Phase analysis and thermal stability of hot isostatically pressed zirconia-hydroxyapatite composites", vol. 83, no. 11, 1 November 2000 (2000-11-01), pages 2798 - 2802, XP008159032, ISSN: 0002-7820, Retrieved from the Internet [retrieved on 20041220], DOI: 10.1111/J.1151-2916.2000.TB01634.X
MIAO X ET AL: "Spark plasma sintered hydroxyapatite-yttria stabilized zirconia composites", CERAMICS INTERNATIONAL, ELSEVIER, AMSTERDAM, NL, vol. 30, no. 7, 1 January 2004 (2004-01-01), pages 1793 - 1796, XP004534341, ISSN: 0272-8842, DOI: 10.1016/J.CERAMINT.2003.12.117
SHUFENG LI ET AL: "Fabrication of hydroxyapatite- incorporated ZrO2-20 wt% Al2O3 by spark plasma sintering and characterization", JOURNAL OF COMPOSITE MATERIALS, SAGE PUBLICATIONS, USA, vol. 43, no. 14, 1 July 2009 (2009-07-01), pages 1503 - 1517, XP008159039, ISSN: 0021-9983, [retrieved on 20090603]
GAO ET AL.: "Fabrication of HAp-Zr02 (3Y) nano-composite by SPS", BIOMATERIALS, vol. 24, 2003, pages 937 - 940, XP004399586
ERIK ADOLFSSON ET AL: "Phase analysis and thermal stability of hot isostatically pressed zirconia-hydroxyapatite composites", vol. 83, no. 11, 1 November 2000 (2000-11-01), pages 2798 - 2802, XP008159032, ISSN: 0002-7820, Retrieved from the Internet
MIAO X ET AL: "Spark plasma sintered hydroxyapatite-yttria stabilized zirconia composites", CERAMICS INTERNATIONAL, ELSEVIER, AMSTERDAM, NL, vol. 30, no. 7, 1 January 2004 (2004-01-01), pages 1793 - 1796, XP004534341, ISSN: 0272-8842, DOI: 10.1016/J.CERAMINT.2003.12.117
SHUFENG LI ET AL: "Fabrication of hydroxyapatite- incorporated ZrO2-20 wt% Al2O3 by spark plasma sintering and characterization", JOURNAL OF COMPOSITE MATERIALS, SAGE PUBLICATIONS, USA, vol. 43, no. 14, 1 July 2009 (2009-07-01), pages 1503 - 1517, XP008159039, ISSN: 0021-9983, [retrieved on 20090603]
Attorney, Agent or Firm:
ROMAN EKSTEDT, Måns (P.O. Box 5190, Gothenburg, SE)
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