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Title:
COMPOSITION FOR AMELIORATING COGNITIVE FUNCTIONS IN DEMENTIA
Document Type and Number:
WIPO Patent Application WO/2019/221165
Kind Code:
A1
Abstract:
The present invention pertains to a composition that is for ameliorating brain functions and that contains coral calcium, a cinnamic acid derivative compound, and a nicotine amide derivative.

Inventors:
HASEGAWA TORU (JP)
Application Number:
PCT/JP2019/019256
Publication Date:
November 21, 2019
Filing Date:
May 15, 2019
Export Citation:
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Assignee:
HASEGAWA TORU (JP)
NOGUCHI HIROSHI (JP)
International Classes:
A23L33/10; A23L33/105; A23L33/16; A61K31/01; A61K31/192; A61K31/375; A61K31/7084; A61K33/00; A61K35/614; A61K36/185; A61K36/232; A61K36/82; A61P25/28; A61P43/00
Domestic Patent References:
WO2015016285A12015-02-05
Other References:
ANDERSON, D. W. ET AL.: "Broad neuroprotective profile of nicotinamide in different mouse models of MPTP-induced parkinsonism", EUROPEAN JOURNAL OF NEUROSCIENCE, vol. 28, 2008, pages 610 - 617, XP055654284
HOU, YUJUN ET AL.: "NAD+ supplementation normalizes key Alzheimer' s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency", PNAS, 5 February 2018 (2018-02-05), pages E1876 - E1885, XP055654286
"GPR109A and Parkinson's Disease: Role of Niacin in Outcome Measures", HISTORY OF CHANGES FOR STUDY: NCT03462680, CLINICALTRIALS.GOV ARCHIVE, vol. 1, 5 March 2018 (2018-03-05), pages 1 - 8, XP055654295, Retrieved from the Internet
MORRIS, M. C. ET AL.: "Dietary niacin and the risk of incident Alzheimer's disease and of cognitive decline", J. NEUROL. NEUROSURG. PSYCHIATRY, vol. 75, 2004, pages 1093 - 1099, XP008113217, DOI: 10.1136/jnnp.2003.025858
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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