Title:
COMPOSITION FOR AMELIORATING OR TREATING ALZHEIMER'S DEMENTIA, COMPRISING TETRAGONIA TETRAGONIOIDES AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2021/085741
Kind Code:
A1
Abstract:
The present invention relates to a composition for preventing or ameliorating Alzheimer's dementia, comprising a Tetragonia teragonioides extract as an active ingredient. By using this, accumulation of β-amyloids in the brain tissue is prevented, expression of brain-derived neurotrophic factor (BDNF) and ciliary neurotrophic factor (CNTF) genes is increased, and expression of Tau genes forming neurofibrillary tangles (MTF), known as a cause of Alzheimer's dementia, is reduced, thereby preventing, ameliorating or treating Alzheimer's dementia, specifically of β-amyloid accumulation type and Tau protein accumulation type.
Inventors:
KO BYOUNG SEOB (KR)
RYUK JIN AH (KR)
PARK SUNMIN (KR)
RYUK JIN AH (KR)
PARK SUNMIN (KR)
Application Number:
PCT/KR2019/017420
Publication Date:
May 06, 2021
Filing Date:
December 11, 2019
Export Citation:
Assignee:
KOREA INST ORIENTAL MEDICINE (KR)
International Classes:
A23L33/105; A61K36/185; A61P25/28
Foreign References:
| KR20160071155A | 2016-06-21 | |||
| KR20190016754A | 2019-02-19 | |||
| JP2017145221A | 2017-08-24 | |||
| KR20190040172A | 2019-04-17 | |||
| KR20140120667A | 2014-10-14 |
Attorney, Agent or Firm:
CHOI, Kyu Whan (KR)
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