A COMPOSITION COMPRISING AJOENE FOR PREVENTING OR TREATING A DISEASE CAUSED BY OVEREXPRESSION OF LXR-ALPHA

WIPO Patent Application WO/2011/122805

A2

The present invention is related to a composition comprising the ajoene -abundant garlic extract or ajoene isolated therefrom as an active ingredient for treating or preventing the disease caused by over-expression or hyper-activation of LXR-alpha or SREBP-1, together with a pharmaceutically acceptable carrier.

KIM, Sang Geon (#102-206, Gangchon Apt. 402, Ichon-dong, Youngsan-gu, Seoul 140-030, KR)
RYU, Jae Ha (#601-402, Mokdong Apt. 911, Mok-dong, Yangcheon-gu, Seoul 158-050, KR)
JEON, Ra Ok (# Gaepowoosung Apt, Daechi 1-dong Gangnam-gu, Seoul 135-281, 3-1105, KR)
HAN, Chang Yeob (#302, 1642-19 Inhun-dong, Gwanak-gu, Seoul 151-061, KR)

KR2011/002094

October 06, 2011

March 25, 2011

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SNU R&DB FOUNDATION (#56-1, San Sillim-dong, Gwanak-gu, Seoul 151-015, KR)
KIM, Sang Geon (#102-206, Gangchon Apt. 402, Ichon-dong, Youngsan-gu, Seoul 140-030, KR)
RYU, Jae Ha (#601-402, Mokdong Apt. 911, Mok-dong, Yangcheon-gu, Seoul 158-050, KR)
JEON, Ra Ok (# Gaepowoosung Apt, Daechi 1-dong Gangnam-gu, Seoul 135-281, 3-1105, KR)
HAN, Chang Yeob (#302, 1642-19 Inhun-dong, Gwanak-gu, Seoul 151-061, KR)

A61K36/8962; A61P1/16; A61P3/00; A61P9/12

SHIN, Dong In (#503, V-Charmant Bldg.1601-1, Seocho 3-dong, Seocho-gu, Seoul 137-953, KR)

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