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Title:
COMPOSITION COMPRISING ALPHA-GARCINIA MANGOSTANA, BETA-GARCINIA MANGOSTANA, GAMMA-GARCINIA MANGOSTANA, OR GARTANIN COMPOUND AS EFFECTIVE INGREDIENT FOR IMPROVING SKIN WRINKLE OR FOR MOISTURIZING SKIN
Document Type and Number:
WIPO Patent Application WO/2017/217695
Kind Code:
A1
Abstract:
The present invention relates to a composition comprising at least one compound selected from among an alpha-Garcinia mangostana compound, a beta-Garcinia mangostana compound, a gamma-Garcinia mangostana compound, and a gartanin compound as an effective ingredient for improving skin wrinkles. More particularly, an alpha-Garcinia mangostana compound, a beta-Garcinia mangostana compound, a gamma-Garcinia mangostana compound, and a gartanin compound increase expression levels of involucrin, filaggrin, and loricrin all of which can suppress ultraviolet-induced cell injury, can significantly inhibit the expression of MMP-1 and MMP-9, and can enhance skin moisturization. Hence, the composition of the present invention may be used as a cosmetic material for improving skin wrinkles or moisturizing the skin, as a pharmaceutical composition for preventing or treating skin wrinkles, or as a health functional food composition for improving skin wrinkles or for anti-aging.

Inventors:
CHAE SUNG WOOK (KR)
IM A RANG (KR)
Application Number:
PCT/KR2017/005957
Publication Date:
December 21, 2017
Filing Date:
June 08, 2017
Export Citation:
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Assignee:
KOREA INST ORIENTAL MEDICINE (KR)
International Classes:
A61K8/49; A23L33/10; A61K31/352; A61Q19/08
Foreign References:
JP2003252745A2003-09-10
JP2007106674A2007-04-26
JP5020475B22012-09-05
KR101299013B12013-08-23
KR20170062222A2017-06-07
Other References:
KIM, GI PPEUM ET AL.: "Synergetic Effects of Sericin and Alpha-Mangostin on Anti-wrinkle Effects", KOREAN EDUCATION JOURNAL OF AESTHETIC SOCIETY, vol. 13, no. 6, 2015, pages 729 - 734, XP055449344
Attorney, Agent or Firm:
CHOI, Kyu Whan (KR)
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