Title:
COMPOSITION COMPRISING BACILLUS CALMETTE GUERIN POLYSACCHARIDES AND BACILLUS CALMETTE GUERIN NUCLEIC ACIDS AND USE OF PREPARING MEDICAMENT THEREOF
Document Type and Number:
WIPO Patent Application WO/2010/081257
Kind Code:
A1
Abstract:
A composition comprising Bacillus Calmette Guerin polysaccharides and Bacillus Calmette Guerin nucleic acids is provided, wherein said polysaccharides are comprising 10%-69% by mass of the composition and said nucleic acids are comprising 30%-89% by mass of the composition. The composition is made by mixing said polysaccharides and said nucleic acids, wherein said polysaccharides and said nucleic acids are obtained from the Bacillus Calmette Guerin cultures by the following process: extracting the mixture of said polysaccharides and said nucleic acids from said Bacillus Calmette Guerin cultures, and separating said polysaccharides and said nucleic acids from the mixture by ion exchange chromatography. The use of the composition comprising said polysaccharides and said nucleic acids for preparation of a biological medicament for treatment or prevention of microorganism infections, tumors, allergic reactions and the like is also provided.
Inventors:
NING YUNSHAN (CN)
GUAN JIFENG (CN)
GUAN JIFENG (CN)
Application Number:
PCT/CN2009/000069
Publication Date:
July 22, 2010
Filing Date:
January 16, 2009
Export Citation:
Assignee:
JIUZHITANG CO LTD (CN)
NING YUNSHAN (CN)
GUAN JIFENG (CN)
NING YUNSHAN (CN)
GUAN JIFENG (CN)
International Classes:
A61K39/04; A61K31/7052; A61K31/715; A61P31/00; A61P35/00; A61P37/00; A61P37/08
Foreign References:
| CN1494918A | 2004-05-12 |
Other References:
HENG BAOYAN ET AL.: "Clinical investigation of preventive effect of BCG-Polysaccharide Nucleic acid in 102 children with repeated child bronchial asthma", HAINAN MEDICAL JOURNAL, vol. 15, no. 10, 2004, pages 27 - 28
Attorney, Agent or Firm:
LIAN & LIEN IP ATTORNEYS (10th Floor No.33 Anding Road, Chaoyang District, Beijing 9, CN)
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