Title:
COMPOSITION COMPRISING CRASSIRHIZOMAE RHIZOMA EXTRACT AS ACTIVE INGREDIENT FOR PREVENTING, ALLEVIATING, OR TREATING HYPERURICEMIA OR HYPERURICEMIA-RELATED METABOLIC DISORDERS
Document Type and Number:
WIPO Patent Application WO/2018/066952
Kind Code:
A1
Abstract:
The present invention relates to a composition comprising a Crassirhizomae Rhizoma extract as an active ingredient for preventing, alleviating, or treating hyperuricemia or hyperuricemia-related metabolism disorders. The Crassirhizomae Rhizoma extract of the present invention has effects of reducing the serum uric acid content in animal models as well as inhibiting activity of xanthine oxidase. The Crassirhizomae Rhizoma extract is safe and a raw material therefor is relatively easy to supply since the extract is an active ingredient derived from a natural material, so that the extract can be widely utilized in industries associated with hyperuricemia or hyperuricemia-related metabolic disorders. Particularly, the extract can be effectively used in the prevention, alleviation, or treatment of gout or gouty arthritis.
Inventors:
KIM DONG SEON (KR)
LEE YOUNG-SIL (KR)
SON EUN JUNG (KR)
LEE YUN MI (KR)
KIM OHN SOON (KR)
LEE YOUNG-SIL (KR)
SON EUN JUNG (KR)
LEE YUN MI (KR)
KIM OHN SOON (KR)
Application Number:
PCT/KR2017/011041
Publication Date:
April 12, 2018
Filing Date:
September 29, 2017
Export Citation:
Assignee:
KOREA INST ORIENTAL MEDICINE (KR)
International Classes:
A23L33/00; A23L33/105; A61K36/12
Foreign References:
| KR100992601B1 | 2010-11-08 | |||
| KR101457117B1 | 2014-11-04 | |||
| KR101590842B1 | 2016-02-01 |
Other References:
YANG, YANYAN: "ERK1-and TBK1-targeted anti-inflammatory activity of an ethanol extract of Dryopteris crassirhizoma", JOURNAL OF ETHNOPHARMACOLOGY, vol. 145, no. 2, 2013, pages 499 - 508, XP055604736, DOI: 10.1016/j.jep.2012.11.019
HA, HYUNIL: "Water extract of Dryopteris crassirhizoma attenuates bone loss by suppressing osteoclast differentiation and function", EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2013, pages 1 - 10, XP055604738, ISBN: 1741-427x, DOI: 10.1155/2013/852648
HA, HYUNIL: "Water extract of Dryopteris crassirhizoma attenuates bone loss by suppressing osteoclast differentiation and function", EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2013, pages 1 - 10, XP055604738, ISBN: 1741-427x, DOI: 10.1155/2013/852648
Attorney, Agent or Firm:
CHOI, Kyu Whan (KR)
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