Title:
COMPOSITION COMPRISING CUDRANIA TRICUSPIDATE AS EFFECTIVE COMPONENT FOR ALLEVIATING, TREATING, OR PREVENTING MUSCULAR DISEASES, OR IMPROVING MUSCULE FUNCTIONS
Document Type and Number:
WIPO Patent Application WO/2020/246863
Kind Code:
A1
Abstract:
The present invention relates to a composition for preventing and treating muscular diseases, or improving muscle functions, which comprises Cudrania tricuspidate, such as a ground product or an extract thereof, as an effective component. Cudrania tricuspidate, such as the ground product or the extract thereof according to the present invention, has an effect of increasing mTOR activity while downregulating the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation; increases muscle mass; and improves muscle functions, and thus may be usefully utilized in the prevention, alleviation or treatment of various muscular diseases such as atony, muscular atrophy, muscular dystrophy, muscular degeneration, muscle weakness, cachexia, and sarcopenia.
Inventors:
HWANG JAE KWAN (KR)
KIM CHANG HEE (KR)
YOO JI HEE (KR)
KIM CHANG HEE (KR)
YOO JI HEE (KR)
Application Number:
PCT/KR2020/007411
Publication Date:
December 10, 2020
Filing Date:
June 08, 2020
Export Citation:
Assignee:
UNIV YONSEI IACF (KR)
International Classes:
A23L33/105; A61K8/9789; A61K36/605; A61P21/00; A61Q19/00
Foreign References:
| KR20180071721A | 2018-06-28 | |||
| KR20150029852A | 2015-03-19 | |||
| JP2018502119A | 2018-01-25 | |||
| KR20110036317A | 2011-04-07 | |||
| KR20100064156A | 2010-06-14 |
Attorney, Agent or Firm:
CHUNG HYUN PATENT & LAW FIRM (KR)
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