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Title:
COMPOSITION COMPRISING DENDROPANAX MORBIFERA EXTRACT OR COMPOUND DERIVED THEREFROM AS ACTIVE INGREDIENT FOR PREVENTING AND TREATING BENIGN PROSTATIC HYPERPLASIA
Document Type and Number:
WIPO Patent Application WO/2014/014177
Kind Code:
A1
Abstract:
The present invention relates to the use of Dendropanax morbifera extract as an agent for preventing and treating benign prostatic hyperplasia. More particularly, the present invention relates to a composition for preventing and treating benign prostatic hyperplasia and to a functional health food for preventing and reducing the effects of benign prostatic hyperplasia, wherein the composition and food comprise, as an active ingredient, Dendropanax morbifera extract or a compound which is isolated from the extract and then purified. According to the present invention, Dendropanax morbifera extract and the compound isolated from the extract have been demonstrated to be capable of effectively preventing and treating benign prostatic hyperplasia through a mechanism for inhibiting the androgen receptor signaling that induces benign prostatic hyperplasia. Therefore, the Dendropanax morbifera extract and the compound isolated from the extract according to the present invention can be effectively used in the production of medicines and functional foods capable of preventing, treating, and reducing the effects of benign prostatic hyperplasia and prostate cancer.

Inventors:
CHOI CHEOL-HEE (KR)
MOON YOUNG-SOOK (KR)
HAN JU-HEE (KR)
LEE KYOUNG-IN (KR)
KIM HYUN-JUNG (KR)
Application Number:
PCT/KR2013/000766
Publication Date:
January 23, 2014
Filing Date:
January 30, 2013
Export Citation:
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Assignee:
UNIV CHOSUN IACF (KR)
International Classes:
A61K36/25; A61P13/08
Foreign References:
KR100318019B12002-07-03
KR20060131360A2006-12-20
KR20040107853A2004-12-23
Other References:
CHOE, YONG HWAN: "Studies on the Isolation and Analysis of Korean Golden Varnish (Hwangchil) Exudates of Dendropanax morbifera lev", HANBAT UNIVERSITY MASTERS'S THESIS, 2003
PARK, B. -Y. ET AL.: "Isolation and anticomplement activity of compounds from Dendropanax morbifera", JOURNAL OF ETHNOPHARMACOLOGY, vol. 90, 2004, pages 403 - 408
Attorney, Agent or Firm:
WIE, Byoung-Gab (KR)
위병갑 (KR)
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