COMPOSITION COMPRISING THE EXTRACT OF HERBAL COMBINATION FOR PREVENTING OR TREATING DIABETIC PERIPHERAL NEUROPATHY

Title:

COMPOSITION COMPRISING THE EXTRACT OF HERBAL COMBINATION FOR PREVENTING OR TREATING DIABETIC PERIPHERAL NEUROPATHY

Document Type and Number:

WIPO Patent Application WO/2012/124888

Kind Code:

A3

Abstract:

Disclosed are a pharmaceutical composition and a health functional food for the prevention and treatment of diabetic peripheral neuropathy, comprising an herb extract of a mixture of 3.5:1 Dioscorea Rhizoma : Dioscorea nipponica (w/w). Having the ability to synergistically increase in vivo levels of nerve growth factor, compared to the extracts from the herbs alone or herb mixtures of other weight ratios, the mixed herb extract is effective for preventing the apoptosis of nerve cells and promoting nerve regeneration. Thus, it can be applied to pharmaceutical compositions and health functional foods preventive and curative of diabetic peripheral neuropathy.

Inventors:

KIM SOON-HOE (KR)
SON MI-WON (KR)
CHOI SANG-ZIN (KR)
KIM HYE-JU (KR)
RYU JA-YOUNG (KR)
KIM SUN-YEOU (KR)

Application Number:

PCT/KR2011/010294

Publication Date:

November 08, 2012

Filing Date:

December 29, 2011

Export Citation:

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Assignee:

DONG A PHARM CO LTD (KR)
KIM SOON-HOE (KR)
SON MI-WON (KR)
CHOI SANG-ZIN (KR)
KIM HYE-JU (KR)
RYU JA-YOUNG (KR)
KIM SUN-YEOU (KR)

International Classes:

A61K36/8945; A61P3/10; A61P25/00

Foreign References:

KR100854621B1	2008-08-27
KR100811683B1	2008-03-11
KR20100002668A	2010-01-07
KR20100084926A	2010-07-28

Other References: