COMPOSITION COMPRISING HORSE CHESTNUT EXTRACT

WIPO Patent Application WO/2023/033535

A1

The present invention relates to a pharmaceutical composition for preventing or treating periodontal disease, comprising horse chestnut extract as effective component, and a food composition for preventing or improving periodontal disease, comprising horse chestnut extract as effective component, wherein the horse chestnut extract comprises avicularin and juglanin as active ingredients.

KIM MIN YOUNG (KR)
PARK BYUNG YOUNG (KR)
CHO IL HWAN (KR)
PARK EUN KYU (KR)

PCT/KR2022/013018

March 09, 2023

August 31, 2022

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ANGIOLAB INC (KR)

A61K36/185; A23L33/105; A61K8/9789; A61K31/7048; A61P1/02; A61Q11/00

WO2014147613A1	2014-09-25
WO2019125058A1	2019-06-27

JP2006282562A

2006-10-19

IDRIS SAHAR, MISHRA ANURADHA, KHUSHTAR MOHD: "Phytochemical, ethanomedicinal and pharmacological applications of escin from Aesculus hippocastanum L . towards future medicine", JOURNAL OF BASIC AND CLINICAL PHYSIOLOGY AND PHARMACOLOGY, FREUND PUBLISHING HOUSE LTD., LONDON, GB, vol. 31, no. 5, 1 September 2020 (2020-09-01), GB , XP093042469, ISSN: 0792-6855, DOI: 10.1515/jbcpp-2019-0115
CHEN XINXIN, ZHANG CHENGYONG, WANG XIAO, HUO SHOUSONG: "Juglanin inhibits IL-1β-induced inflammation in human chondrocytes", ARTIFICIAL CELLS, NANOMEDICINE AND BIOTECHNOLOGY, TAYLOR & FRANCIS INC., US, vol. 47, no. 1, 4 December 2019 (2019-12-04), US , pages 3614 - 3620, XP093042472, ISSN: 2169-1401, DOI: 10.1080/21691401.2019.1657877

PARK, Jong Hyeok (KR)

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