Title:
COMPOSITION COMPRISING LOCAL ANESTHETIC AND SODIUM POLYACRYLATE
Document Type and Number:
WIPO Patent Application WO/2020/032616
Kind Code:
A1
Abstract:
The present invention relates to a transdermal absorption preparation which comprises lidocaine or a pharmaceutically acceptable salt thereof, and sodium polyacrylate having a substitution degree of sodium of 55 mol% or more, and does not comprise an aqueous sorbitol solution and an aqueous polyacrylic acid solution. The transdermal absorption preparation according to the present invention exhibits excellent transdermal permeability and high elution rate of lidocaine, and enhanced appearance stability, and can be aged at room temperature in a packing state, and thus does not require large-scale equipment for aging the preparation at a high temperature. Therefore, the time and cost for mass-production of the preparation can be remarkably reduced.
Inventors:
JANG JUNHEE (KR)
LEE IN-HYUN (KR)
SONG IN-BEOM (KR)
LEE JI-YEON (KR)
LEE IN-HYUN (KR)
SONG IN-BEOM (KR)
LEE JI-YEON (KR)
Application Number:
PCT/KR2019/009963
Publication Date:
February 13, 2020
Filing Date:
August 08, 2019
Export Citation:
Assignee:
DAE HWA PHARMA CO LTD (KR)
International Classes:
A61K9/00; A61K31/167; A61K47/10; A61K47/18; A61K47/32; A61K47/42; A61P23/02
Foreign References:
| CN102018696A | 2011-04-20 | |||
| KR20020039544A | 2002-05-27 | |||
| US5827529A | 1998-10-27 | |||
| KR20040084783A | 2004-10-06 | |||
| JP2013116861A | 2013-06-13 |
Attorney, Agent or Firm:
CHOI, Eun Sun (KR)
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