Title:
COMPOSITION COMPRISING SCHISANDRA CHINENSIS EXTRACT AS EFFECTIVE INGREDIENT FOR PREVENTION, ALLEVIATION, OR TREATMENT OF ARTHRITIS
Document Type and Number:
WIPO Patent Application WO/2019/177327
Kind Code:
A1
Abstract:
The present invention relates to a composition comprising an extract from Schisandra chinensis leaves or stems as an effective ingredient for prevention, alleviation, or treatment of arthritis. Specifically, the extract from Schisandra chinensis leaves or stems according to the present invention is not cytotoxic, has an effect of inhibiting inflammation-inducted NO production, reduces a thickness of a foot swollen by gout arthritis, and decreases a content of IL-1β. The extract from Schisandra chinensis leaves according to the present invention has an effect of increasing weight bearing reduced in an osteoarthritis animal model with a statistical significance. Thus, the extract can be usefully availed for prevention, alleviation, or treatment of arthritis.
Inventors:
KIM DONG SEON (KR)
LEE YUN MI (KR)
SON EUN JUNG (KR)
YUK HEUNG JOO (KR)
LEE YUN MI (KR)
SON EUN JUNG (KR)
YUK HEUNG JOO (KR)
Application Number:
PCT/KR2019/002819
Publication Date:
September 19, 2019
Filing Date:
March 12, 2019
Export Citation:
Assignee:
KOREA INST ORIENTAL MEDICINE (KR)
International Classes:
A23L33/105; A61K36/79; A61P19/02
Foreign References:
| KR20170045463A | 2017-04-27 | |||
| KR20050014615A | 2005-02-07 | |||
| KR20150067585A | 2015-06-18 | |||
| KR20150115414A | 2015-10-14 | |||
| KR20110036317A | 2011-04-07 |
Attorney, Agent or Firm:
CHOI, Kyu Whan (KR)
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