Title:
COMPOSITION COMPRISING SELAGINELLA ROSSII WARB. EXTRACT OR FRACTIONS THEREOF FOR PREVENTING OR TREATING METABOLIC SYNDROMES
Document Type and Number:
WIPO Patent Application WO/2019/124803
Kind Code:
A1
Abstract:
The present invention provides a composition for preventing, improving, or treating metabolic syndromes comprising Selaginella rossii Warb. extract, fractions thereof, or both as active ingredients. The composition of the present invention strongly inhibits diphenylpeptidase-4(DPP-4), induces increased secretion of insulin in pancreatic beta cells, promotes increased secretion of GLP-1, inhibits fat accumulation in adipocytes, effectively inhibits oxidation of low density lipoprotein(LDL), improves weight gain, improves hyperglycemia and glucose tolerance by high fat diet, lowers blood triglyceride levels, and shows liver protection efficacy. Thus, the present invention can be effectively used for preventing or treating metabolic syndromes as well as has excellent antioxidant activity and can be effectively used as an antioxidant composition.
Inventors:
JEONG TAE SOOK (KR)
PARK HO YONG (KR)
LI HUA (KR)
PIAO RENZHE (CN)
LEE SANG WOO (KR)
CHOI SANG HO (KR)
LI HULIN (CN)
KIM EUN JIN (KR)
PARK HO YONG (KR)
LI HUA (KR)
PIAO RENZHE (CN)
LEE SANG WOO (KR)
CHOI SANG HO (KR)
LI HULIN (CN)
KIM EUN JIN (KR)
Application Number:
PCT/KR2018/014960
Publication Date:
June 27, 2019
Filing Date:
November 29, 2018
Export Citation:
Assignee:
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
International Classes:
A61K36/11; A23L33/105; A61P3/00; A61P3/04; A61P3/10
Foreign References:
| KR20130113626A | 2013-10-16 | |||
| KR20160116427A | 2016-10-10 | |||
| KR20130081852A | 2013-07-18 | |||
| KR20140002262U | 2014-04-22 |
Attorney, Agent or Firm:
PCR INTELLECTUAL PROPERTY LAW FIRM (KR)
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