Title:
COMPOSITION CONTAINING 1H-PYRAZOLE-3-AMIDE-BASED COMPOUND DERIVATIVE FOR PREVENTION OR TREATMENT OF FIBROSIS
Document Type and Number:
WIPO Patent Application WO/2019/054740
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for prevention or treatment of fibrosis or a health functional food composition for prevention or alleviation of fibrosis, each composition containing a 1H-pyrazole-3-amide-based compound or a pharmaceutically acceptable salt thereof as an active ingredient. The compound exhibits a fibrosis mitigation effect in fibrosis-induced mouse models, and thus the compositions containing the compound as an active ingredient can be favorably utilized for prevention or treatment of fibrosis.
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Inventors:
KIM WOOK (KR)
YOON SUNG-HWA (KR)
HAN JI HYE (KR)
SHIN HAN HO (KR)
PARK JU-YOUNG (KR)
YOON SUNG-HWA (KR)
HAN JI HYE (KR)
SHIN HAN HO (KR)
PARK JU-YOUNG (KR)
Application Number:
PCT/KR2018/010671
Publication Date:
March 21, 2019
Filing Date:
September 12, 2018
Export Citation:
Assignee:
TSD LIFE SCIENCES CO LTD (KR)
International Classes:
A61K31/415; A23L33/10
Foreign References:
| KR20090107015A | 2009-10-12 | |||
| KR20100083333A | 2010-07-22 | |||
| KR20130094341A | 2013-08-23 | |||
| US20070213302A1 | 2007-09-13 |
Other References:
TEIXEIRA-CLERC, F. ET AL.: "CB1 Cannabinoid Receptor Antagonism: a New Strategy for the Treatment of Liver Fibrosis", NATURE MEDICINE, vol. 12, no. 6, 2006, pages 671 - 676, XP055583635
SON, M-H ET AL.: "Peripherally Acting CB 1-recepior Antagonist: the Relative Importance of Central and Peripheral CB1 Receptors in Adiposity Control", INTERNATIONAL JOURNAL OF OBESITY, vol. 34, 2010, pages 547 - 556, XP055583637
SON, M-H ET AL.: "Peripherally Acting CB 1-recepior Antagonist: the Relative Importance of Central and Peripheral CB1 Receptors in Adiposity Control", INTERNATIONAL JOURNAL OF OBESITY, vol. 34, 2010, pages 547 - 556, XP055583637
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
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