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Title:
COMPOSITION CONTAINING EICOSAPENTAENOIC ACID ALKYL ESTER, AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2016/043251
Kind Code:
A1
Abstract:
 Provided are: a composition containing 96-99 area% of eicosapentaenoic acid alkyl ester, the composition having an arachidonic acid alkyl ester content of 0.7 area% or less, and an eicosapentaenoic-acid-alkyl-ester mono-trans isomer content of 2.5 area% or less; and a method for producing a composition containing a high concentration of eicosapentaenoic acid alkyl ester, the method including performing precision distillation on a composition containing eicosapentaenoic acid alkyl ester, obtained by alkyl esterification of a raw material oil containing eicosapentaenoic acid, under a vacuum of 0.2 Torr or lower and a temperature of 190°C or lower in the entire column, and performing a concentration treatment on the precision-distilled composition using chromatography.

Inventors:
DOISAKI NOBUSHIGE (JP)
ARATO SHINGO (JP)
FUKAE TAKURO (JP)
Application Number:
PCT/JP2015/076380
Publication Date:
March 24, 2016
Filing Date:
September 17, 2015
Export Citation:
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Assignee:
NIPPON SUISAN KAISHA LTD (JP)
MOCHIDA PHARM CO LTD (JP)
International Classes:
C11C3/10; A61K31/232; A61P3/06; A61P7/02; A61P9/10; C07C67/03; C07C67/54; C07C67/56; C07C69/587; C11B3/12
Domestic Patent References:
WO2014054435A12014-04-10
Foreign References:
JPH05222392A1993-08-31
JP2014510165A2014-04-24
JP2001303089A2001-10-31
JPH08100191A1996-04-16
JPH0441457A1992-02-12
Other References:
See also references of EP 3196280A4
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)
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