Title:
COMPOSITION CONTAINING INDENE COMPOUND AS ACTIVE INGREDIENT FOR BONE REGENERATION AND PREVENTING OR TREATING BONE DISORDERS
Document Type and Number:
WIPO Patent Application WO/2019/083301
Kind Code:
A1
Abstract:
The present invention relates to a composition containing indene derivative as an active ingredient for inducing bone regeneration and preventing or treating bone disorders, the compound capable of stimulating differentiation of osteoblasts and inhibiting differentiation of osteoclasts, thus leading to regeneration or formation of bone. Therefore, the present invention can be effectively used as a pharmaceutical composition for preventing or treating bone disorders, or as preventative or ameliorative health food.
Inventors:
PARK EUI KYUN (KR)
KIM JU ANG (KR)
KIM JU ANG (KR)
Application Number:
PCT/KR2018/012731
Publication Date:
May 02, 2019
Filing Date:
October 25, 2018
Export Citation:
Assignee:
KYUNGPOOK NAT UNIV IND ACADEMIC COOP FOUND (KR)
International Classes:
A61K31/16; A23L33/10; A61K31/215
Domestic Patent References:
| WO2009038731A2 | 2009-03-26 |
Foreign References:
| KR20050100052A | 2005-10-18 | |||
| KR20110028050A | 2011-03-17 | |||
| US20030166643A1 | 2003-09-04 | |||
| US4218472A | 1980-08-19 |
Other References:
KIM, J. A.: "Magnesium phosphate ceramics incorporating a novel indenecompound promote osteoblast differentiation in vitro and boneregeneration in vivo", BIOMATERIALS, 7 December 2017 (2017-12-07), pages 51 - 61, XP055598251
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
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