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Title:
COMPOSITION CONTAINING LACTIC ACID BACTERIUM PRODUCING EQUOL
Document Type and Number:
WIPO Patent Application WO/2005/000042
Kind Code:
A1
Abstract:
It is intended to provide a composition containing a lactic acid-bacterium producing equol characterized by containing a lactic acid bacterium belonging to the genus Lactococcus that is capable of metabolizing at least one daidzein compound selected from the group consisting of daidzein glycosides, daidzein and dihydrodaidzein and thus producing equol; and a process for producing equol characterized by comprising treating at least one member selected from the group consisting of daidzein compounds and daidzein-containing materials with the lactic acid bacterium as described above. The above-described lactic acid bacterium includes Lactococcus garvieae. This composition is efficacious in preventing and relieving indefinite complaints including menopausal disorders in middle-aged and older women.

Inventors:
UCHIYAMA SHIGETO (JP)
UENO TOMOMI (JP)
SUZUKI TOSHIMI (JP)
Application Number:
PCT/JP2004/009484
Publication Date:
January 06, 2005
Filing Date:
June 29, 2004
Export Citation:
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Assignee:
OTSUKA PHARMA CO LTD (JP)
UCHIYAMA SHIGETO (JP)
UENO TOMOMI (JP)
SUZUKI TOSHIMI (JP)
International Classes:
A23C9/123; A23C11/10; A23L1/30; A23L2/52; A23L2/84; A23L11/00; A23L33/135; A61K31/352; A61K31/353; A61K35/74; A61K35/744; A61K36/48; A61P3/06; A61P9/12; A61P15/12; A61P19/10; A61P35/00; C12P17/06; A61K131/00; (IPC1-7): A23L1/30; A23L1/20; C12N1/20; C12P17/06; A61K35/74; A61K35/78; A61P15/12; A61P19/10; A61P35/00
Domestic Patent References:
WO2004009035A22004-01-29
WO1999007392A11999-02-18
Foreign References:
JP2003081855A2003-03-19
Other References:
TAMURA M. ET AL.: "Effects of soy protein-isoflavone diet on plasma isoflavone and intestinal microflora in adult mice", NUTRITION RESEARCH, vol. 22, no. 6, June 2002 (2002-06-01), pages 705 - 713, XP002982247
See also references of EP 1649760A4
Attorney, Agent or Firm:
Saegusa, Eiji (1-7-1 Doshomachi, Chuo-k, Osaka-shi Osaka 45, JP)
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