Title:
COMPOSITION CONTAINING MORI CORTEX RADICIS EXTRACT AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING DEPRESSION
Document Type and Number:
WIPO Patent Application WO/2013/151281
Kind Code:
A1
Abstract:
The present invention provides a composition containing Mori Cortex Radicis extract as an active ingredient for preventing or treating depression. The present invention exhibits an anti-stress effect by suppressing the nuclear translocation of glucocorticoid receptors, thereby impeding a stress-induced signal transmission process, and, similar to existing anti-depressives, can have an anti-depressive effect from an antagonist effect thereof for glucocorticoid receptors. Additionally, the present invention provides a food composition containing Mori Cortex Radicis extract as an active ingredient for improving or mitigating depression.
Inventors:
HAN DAE SEOK (KR)
LEE CHANG-HO (KR)
KIM YOUNG-EON (KR)
KIM IN-HO (KR)
JANG YU JUNG (KR)
HER SONG (KR)
LEE MI SOOK (KR)
CHO SUEONG-MOCK (KR)
KIM YUN TAI (KR)
LEE CHANG-HO (KR)
KIM YOUNG-EON (KR)
KIM IN-HO (KR)
JANG YU JUNG (KR)
HER SONG (KR)
LEE MI SOOK (KR)
CHO SUEONG-MOCK (KR)
KIM YUN TAI (KR)
Application Number:
PCT/KR2013/002657
Publication Date:
October 10, 2013
Filing Date:
March 29, 2013
Export Citation:
Assignee:
KOREA FOOD RES INST (KR)
International Classes:
A61K36/605; A61P25/00
Foreign References:
KR20050067131A | 2005-06-30 | |||
KR20100012735A | 2010-02-08 | |||
KR20100024897A | 2010-03-08 |
Other References:
NADE, VANDANA S. ET AL.: "Adaptogenic effect of Morus alba in chronic foots hock-induced stress in rats", INDIAN JOURNAL OF PHARMACOLOGY, vol. 41, no. 6, 2009, pages 246 - 251
JINTANA STTAYASAI ET AL.: "Biphasic Effects of Morus alba Leaves Green Tea Extract in Mice in Chronic Forced Swimming Model", PHYTOTHERAPY RESEARCH, vol. 22, 2008, pages 487 - 498
JINTANA STTAYASAI ET AL.: "Biphasic Effects of Morus alba Leaves Green Tea Extract in Mice in Chronic Forced Swimming Model", PHYTOTHERAPY RESEARCH, vol. 22, 2008, pages 487 - 498
Attorney, Agent or Firm:
YANG, Boo-Hyun (Chungdong Building1659-2 Inhundong, Gwanak-gu, Seoul 151-832, KR)
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