Title:
COMPOSITION FOR DEGRADING NON-COLLAGENOUS GLYCOPROTEIN
Document Type and Number:
WIPO Patent Application WO/2018/181071
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing an agent for degrading a non-collagenous glycoprotein, a composition for degrading a non-collagenous glycoprotein, a medicinal composition for degrading a non-collagenous glycoprotein and a food or beverage composition for degrading a non-collagenous glycoprotein, each being able to be easily produced and showing no side effects. To solve this problem, provided are an agent for degrading a non-collagenous glycoprotein, a composition for degrading a non-collagenous glycoprotein, a medicinal composition for degrading a non-collagenous glycoprotein and a food or beverage composition for degrading a non-collagenous glycoprotein, each comprising, as an active ingredient, a bacterium belonging to the genus Bifidobacterium, a culture of the bacterium and/or treated cells of the bacterium.
Inventors:
SAKURAI TAKUMA (JP)
HASHIKURA NANAMI (JP)
SHIMIZU KANETADA (JP)
HASHIKURA NANAMI (JP)
SHIMIZU KANETADA (JP)
Application Number:
PCT/JP2018/011923
Publication Date:
October 04, 2018
Filing Date:
March 23, 2018
Export Citation:
Assignee:
MORINAGA MILK INDUSTRY CO LTD (JP)
International Classes:
A61K35/745; A23L33/17; A23L33/195; A61P3/10; A61P7/02; A61P7/04; A61P9/10; A61P11/00; A61P27/02; A61P27/06; A61P43/00; C07K14/745; C12N1/20; C12N9/52; A61K38/48; A61K38/49
Foreign References:
| JP2008519018A | 2008-06-05 | |||
| JP2011132188A | 2011-07-07 | |||
| JP2016519063A | 2016-06-30 | |||
| JP2003238423A | 2003-08-27 | |||
| CN101579361A | 2009-11-18 |
Other References:
JEFFRIES, L. ET AL.: "The detection and differentiation of fibrinolytic enzymes in bacteria.", JOURNAL OF APPLIED BACTERIOLOGY, vol. 49, no. 3, December 1980 (1980-12-01), pages 479 - 492, XP055558584
AHN, M. J. ET AL.: "Characterization of a Novel Fibrinolytic Enzyme, BsfA, from Bacillus subtllls ZA 400 in Klmcbl Reveals Its Pertinence to Thrombosis Treatment.", JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, vol. 25, no. 12, 2015, pages 2090 - 2099, XP055558589
CANDELA, M. ET AL.: "Plasminogen-dependent proteolytic activity in Bifidobacterium lactis.", MICROBIOLOGY, vol. 154, no. 8, 2008, pages 2457 - 2462, XP055558592
WEI, X. ET AL.: "Proteomic analysis of the interaction of Bifidobacterium longum NCC2705 with the intestine cells Caco-2 and identification of plasminogen receptors.", JOURNAL OF PROTEOMICS, vol. 108, 2014, pages 89 - 98, XP029037235
VASTANO, V. ET AL.: "Identification of binding sites of Lactobacillus plantarum enolase involved in the interaction with human plasminogen.", MICROBIOLOGICAL RESEARCH, vol. 168, no. 2, February 2013 (2013-02-01), pages 65 - 72, XP055558597
AHN, M. J. ET AL.: "Characterization of a Novel Fibrinolytic Enzyme, BsfA, from Bacillus subtllls ZA 400 in Klmcbl Reveals Its Pertinence to Thrombosis Treatment.", JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, vol. 25, no. 12, 2015, pages 2090 - 2099, XP055558589
CANDELA, M. ET AL.: "Plasminogen-dependent proteolytic activity in Bifidobacterium lactis.", MICROBIOLOGY, vol. 154, no. 8, 2008, pages 2457 - 2462, XP055558592
WEI, X. ET AL.: "Proteomic analysis of the interaction of Bifidobacterium longum NCC2705 with the intestine cells Caco-2 and identification of plasminogen receptors.", JOURNAL OF PROTEOMICS, vol. 108, 2014, pages 89 - 98, XP029037235
VASTANO, V. ET AL.: "Identification of binding sites of Lactobacillus plantarum enolase involved in the interaction with human plasminogen.", MICROBIOLOGICAL RESEARCH, vol. 168, no. 2, February 2013 (2013-02-01), pages 65 - 72, XP055558597
Attorney, Agent or Firm:
KAWAGUCHI, Yoshiyuki et al. (JP)
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