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Title:
COMPOSITION FOR DEGRADING OPIOID PEPTIDE
Document Type and Number:
WIPO Patent Application WO/2018/181069
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing an agent for degrading an opioid peptide or a composition for degrading an opioid peptide which requires no restriction on diet, shows no side effects even if used regularly and, therefore, can be continuously used free from anxiety. To solve this problem, provided are an agent for degrading an opioid peptide, a composition for degrading an opioid peptide, a medicinal composition for degrading an opioid peptide and a food or beverage composition for degrading an opioid peptide, each comprising, as an active ingredient, a bacterium belonging to the genus Bifidobacterium, a culture of the bacterium and/or treated cells of the bacterium.

Inventors:
SAKURAI TAKUMA (JP)
HASHIKURA NANAMI (JP)
SHIMIZU KANETADA (JP)
YAMADA AKIO (JP)
Application Number:
PCT/JP2018/011920
Publication Date:
October 04, 2018
Filing Date:
March 23, 2018
Export Citation:
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Assignee:
MORINAGA MILK INDUSTRY CO LTD (JP)
International Classes:
A61K35/745; A23L33/135; A61P25/00; A61P43/00; C12N1/00; C12N1/20
Domestic Patent References:
WO2003028745A12003-04-10
WO2013047082A12013-04-04
WO2013047082A12013-04-04
Foreign References:
CN105213433A2016-01-06
CN104011199A2014-08-27
JP3050074B22000-06-05
Other References:
ISHIZEKI, S. ET AL.: "Effect of administration of bifidobacteria on intestinal microbiota in low- birth-weight infants and transition of administered bifidobacteria: A comparison between one-species and three-species administration", ANAEROBE, vol. 23, October 2013 (2013-10-01), pages 38 - 44, XP055558571
WALLACE, R. J. ET AL.: "Peptidase activity of human colonic bacteria", ANAEROBE, vol. 3, 1997, pages 251 - 257, XP055558580
PUSCHEL, G. ET AL.: "Isolation and characterization of dipeptidyl peptidase IV from human placenta", EUR. J. BIOCHEM., vol. 126, no. 2, August 1982 (1982-08-01), pages 359 - 365, XP055558579
M.S. TRIVEDI ET AL., J. NUTR. BIOCHEM., vol. 25, no. 10, 2014, pages 1011 - 1018
A. REISSMANN ET AL., FUNCTIONAL FOODS IN HEALTH AND DISEASE, vol. 4, no. 8, 2014, pages 349 - 361
T-R YAN ET AL., BIOSCI. BIOTECH. BIOCHEM., vol. 56, no. 5, 1992, pages 704 - 707
G. PUSCHEL ET AL., EUR. J. BIOCHEM., vol. 126, no. 2, 1982, pages 359 - 365
SOKOLOV ET AL., PEPTIDES, vol. 56, 2014, pages 68 - 71
J. WASILEWSKA ET AL., NUROPEPTIDES, vol. 45, 2011, pages 189 - 195
See also references of EP 3603655A4
Attorney, Agent or Firm:
KAWAGUCHI, Yoshiyuki et al. (JP)
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