Title:
COMPOSITION FOR DIAGNOSING OVARIAN CANCER, CONTAINING LYSOPHOSPHATIDYLCHOLINE AND HOMOCYSTEIC ACID, AND METHOD FOR DIAGNOZING OVARIAN CANCER BY USING SAME
Document Type and Number:
WIPO Patent Application WO/2015/026171
Kind Code:
A1
Abstract:
The present invention relates to diagnosis of ovarian cancer by using lysophosphatidylcholine (16:0) and homocysteic acid, which are low-mass ions present in a biological sample. The present invention allows ovarian cancer to be diagnosed with accuracy and rapidity at low cost, and thus is expected to be applied to early diagnosis and treatment of ovarian cancer so as to give importance thereto.
Inventors:
KIM SEUNG CHEOL (KR)
YOO BYONG CHUL (KR)
KIM KYUNG-HEE (KR)
KIM YUN HWAN (KR)
YOO BYONG CHUL (KR)
KIM KYUNG-HEE (KR)
KIM YUN HWAN (KR)
Application Number:
PCT/KR2014/007760
Publication Date:
February 26, 2015
Filing Date:
August 21, 2014
Export Citation:
Assignee:
UNIV EWHA IND COLLABORATION (KR)
International Classes:
G01N33/574; G01N33/53; G01N33/92
Foreign References:
| US20020123084A1 | 2002-09-05 | |||
| KR20040062819A | 2004-07-09 |
Other References:
SUTPHEN, R. ET AL.: "Lysophospholipids are potential biomarkers of ovarian cancer", CANCER EPIDEMIOLOGY, BIOMARKERS & PREVENTION, vol. 13, no. 7, 2004, pages 1185 - 1191
LUKYANOVA, N. Y.: "Characteristics of homocysteine-induced multidrug resistance of human MCF-7 breast cancer cells and human A2780 ovarian cancer cells", EXPERIMENTAL ONCOLOGY, vol. 32, no. 1, 2010, pages 10 - 14
SCHULZ, R.-J.: "Homocysteine as a biomarker for cognitive dysfunction in the elderly", CURRENT OPINION IN CLINICAL NUTRITION & METABOLIC CARE, vol. 10, 2007, pages 718 - 723
KIM, S. C . ET AL.: "Differential levels of L-homocysteic acid and lysophosphatidylcholine (16:0) in sera of patients with ovarian cancer", ONCOLOGY LETTERS, vol. 8, 3 June 2014 (2014-06-03), pages 566 - 574
LUKYANOVA, N. Y.: "Characteristics of homocysteine-induced multidrug resistance of human MCF-7 breast cancer cells and human A2780 ovarian cancer cells", EXPERIMENTAL ONCOLOGY, vol. 32, no. 1, 2010, pages 10 - 14
SCHULZ, R.-J.: "Homocysteine as a biomarker for cognitive dysfunction in the elderly", CURRENT OPINION IN CLINICAL NUTRITION & METABOLIC CARE, vol. 10, 2007, pages 718 - 723
KIM, S. C . ET AL.: "Differential levels of L-homocysteic acid and lysophosphatidylcholine (16:0) in sera of patients with ovarian cancer", ONCOLOGY LETTERS, vol. 8, 3 June 2014 (2014-06-03), pages 566 - 574
Attorney, Agent or Firm:
AHN, So-Young (KR)
안소영 (KR)
안소영 (KR)
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