Title:
COMPOSITION FOR DIAGNOSING SUSCEPTIBILITY OF STAPHYLOCOCCUS AUREUS TO ANTIBIOTICS, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/092641
Kind Code:
A1
Abstract:
The present invention relates to a composition for diagnosing the susceptibility of Staphylococcus aureus to antibiotics, and a use thereof. Particularly, it has been ascertained that sosA is a marker specific to (Staphylococcus aureus, and that the expression level of sosA is exhibited similarly to antibiotic susceptibility/resistance properties so as to be usable as a means for diagnosing the susceptibility/resistance of Staphylococcus aureus to antibiotics, and the present invention diagnoses the susceptibility/resistance of Staphylococcus aureus present in samples to antibiotics by using antibodies specifically binding to protein SosA, and thus provides, as a means for diagnosing the susceptibility of Staphylococcus aureus to antibiotics, a composition containing an agent for measuring the mRNA expression level of the sosA gene or an agent for measuring the expression level of the SosA protein.
Inventors:
JANG SOOJIN (KR)
LEE YUNMI (KR)
LEE YUNMI (KR)
Application Number:
PCT/KR2021/014293
Publication Date:
May 05, 2022
Filing Date:
October 15, 2021
Export Citation:
Assignee:
PASTEUR INSTITUT KOREA (KR)
International Classes:
C12Q1/689; C07K16/12; G01N33/569; G01N33/68
Foreign References:
| KR101779038B1 | 2017-09-18 | |||
| KR20200062063A | 2020-06-03 | |||
| KR20200109188A | 2020-09-22 | |||
| KR20200083297A | 2020-07-08 | |||
| KR20050117281A | 2005-12-14 |
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
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