Title:
COMPOSITION OF DIALYSIS LIQUID COMPRISING CRYSTALLISATION INHIBITOR SUBSTANCES
Document Type and Number:
WIPO Patent Application WO/2010/018278
Kind Code:
A3
Abstract:
The present invention relates to a composition comprising phosphate and/or bisphosphonate inositols and their utilisation to prevent loss of substances of biological importance in the organism of patients subjected to dialysis and to maintain physiological levels of said substances sufficient to regulate physiological and/or pathological processes, the substances being inhibitory substances of pathological crystallisation.
Inventors:
GRASES FREIXEDAS FELIX (ES)
PERELLO BESTARD JOAN (ES)
TUR ESPINOSA FERNANDO (ES)
COSTA BAUZA ANTONIA (ES)
PRIETO ALMIRALL RAFAEL M (ES)
GOMILA MUNIZ ISABEL (ES)
PERELLO BESTARD JOAN (ES)
TUR ESPINOSA FERNANDO (ES)
COSTA BAUZA ANTONIA (ES)
PRIETO ALMIRALL RAFAEL M (ES)
GOMILA MUNIZ ISABEL (ES)
Application Number:
PCT/ES2009/070156
Publication Date:
December 16, 2010
Filing Date:
May 14, 2009
Export Citation:
Assignee:
UNIV ILLES BALEARS (ES)
GRASES FREIXEDAS FELIX (ES)
PERELLO BESTARD JOAN (ES)
TUR ESPINOSA FERNANDO (ES)
COSTA BAUZA ANTONIA (ES)
PRIETO ALMIRALL RAFAEL M (ES)
GOMILA MUNIZ ISABEL (ES)
GRASES FREIXEDAS FELIX (ES)
PERELLO BESTARD JOAN (ES)
TUR ESPINOSA FERNANDO (ES)
COSTA BAUZA ANTONIA (ES)
PRIETO ALMIRALL RAFAEL M (ES)
GOMILA MUNIZ ISABEL (ES)
International Classes:
A61K31/66; A61K31/6615; A61K31/663; A61K33/42; A61P7/08
Foreign References:
| US20070148258A1 | 2007-06-28 | |||
| US4752586A | 1988-06-21 |
Other References:
SAEKI TOMOAKI ET AL: "Inositol-1,4,5-trisphosphate increases contractions but not L-type calcium current in guinea pig ventricular myocytes", CARDIOVASCULAR RESEARCH, vol. 41, no. 3, March 1999 (1999-03-01), pages 620 - 628, XP002571970, ISSN: 0008-6363
BOUCHER L ET AL: "INTERNALIZATION AND DISTRIBUTION OF INOSITOL HEXAKISPHOSPHATE IN RED BLOOD CELLS", BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, ACADEMIC PRESS, US, vol. 24, no. PART 01, 1 August 1996 (1996-08-01), pages 73 - 78, XP009045630, ISSN: 0885-4513
GRASES F ET AL: "Effects of phytate and pyrophosphate on brushite and hydroxyapatite crystallization: Comparison with the action of other polyphosphates", UROLOGICAL RESEARCH, vol. 28, no. 2, April 2000 (2000-04-01), pages 136 - 140, XP002571971, ISSN: 0300-5623
GRASES F ET AL: "Phytate inhibits bovine pericardium calcification in vitro", CARDIOVASCULAR PATHOLOGY, ELSEVIER SCIENCE, NEW YORK, NY, US, vol. 17, no. 3, 1 May 2008 (2008-05-01), pages 139 - 145, XP022640076, ISSN: 1054-8807, [retrieved on 20071024]
BOUCHER L ET AL: "INTERNALIZATION AND DISTRIBUTION OF INOSITOL HEXAKISPHOSPHATE IN RED BLOOD CELLS", BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, ACADEMIC PRESS, US, vol. 24, no. PART 01, 1 August 1996 (1996-08-01), pages 73 - 78, XP009045630, ISSN: 0885-4513
GRASES F ET AL: "Effects of phytate and pyrophosphate on brushite and hydroxyapatite crystallization: Comparison with the action of other polyphosphates", UROLOGICAL RESEARCH, vol. 28, no. 2, April 2000 (2000-04-01), pages 136 - 140, XP002571971, ISSN: 0300-5623
GRASES F ET AL: "Phytate inhibits bovine pericardium calcification in vitro", CARDIOVASCULAR PATHOLOGY, ELSEVIER SCIENCE, NEW YORK, NY, US, vol. 17, no. 3, 1 May 2008 (2008-05-01), pages 139 - 145, XP022640076, ISSN: 1054-8807, [retrieved on 20071024]
Attorney, Agent or Firm:
PONS ARIÑO, Angel (Madrid, ES)
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