Title:
COMPOSITION FOR ENHANCING OVARIAN FUNCTION OR PREVENTING OR TREATING OVOTOXICITY
Document Type and Number:
WIPO Patent Application WO/2023/153794
Kind Code:
A1
Abstract:
The present invention relates to a composition for enhancing ovarian function or preventing or treating ovotoxicity. By means of Magnolia Liliflora Bud, Paeonia Lactiflora, Malt, and Astragalus Membranaceus extracts inhibiting the production of active oxygen, it is confirmed that the present invention exhibits an effect of protecting ovarian cells, inhibiting apoptosis, and activating the PI3K/Akt signaling pathway against ovotoxicity induced by VCD, and the present invention can thereby be used for enhancing ovarian function or preventing, treating, or improving ovotoxicity.
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Inventors:
LEE JU-HEE (KR)
KIM DONGIL (KR)
KIM SUN AH (KR)
YOO SEONG KYUNG (KR)
KIM DONGIL (KR)
KIM SUN AH (KR)
YOO SEONG KYUNG (KR)
Application Number:
PCT/KR2023/001830
Publication Date:
August 17, 2023
Filing Date:
February 08, 2023
Export Citation:
Assignee:
DONGGUK UNIV WISE CAMPUS INDUSTRY ACADEMY COOPERATION FOUNDATION (KR)
International Classes:
A61K36/481; A23L33/105; A61K36/65; A61K36/899; A61P15/08; A61P39/06; A61P43/00
Foreign References:
| CN104491594A | 2015-04-08 | |||
| CN105687927A | 2016-06-22 | |||
| CN107213311A | 2017-09-29 | |||
| KR20210043788A | 2021-04-22 | |||
| KR20150030428A | 2015-03-20 | |||
| KR20190042477A | 2019-04-24 |
Other References:
XIE LI; WU SINING; CAO DONGDONG; LI MEIFANG; LIU JIAN; NIE GUANGNING; LI YANG; YANG HONGYAN: "Huyang yangkun formula protects against 4-Vinylcyclohexene diepoxide-induced premature ovarian insufficiency in rats via the Hippo–JAK2/STAT3 signaling pathway", BIOMEDICINE & PHARMACOTHERAPY, ELSEVIER, FR, vol. 116, 1 January 1900 (1900-01-01), FR , XP085712143, ISSN: 0753-3322, DOI: 10.1016/j.biopha.2019.109008
LEE, JU-HEE: "Screening of medicinal herb enhancing ovarian function and analysis of its therapeutic effect against infertility", GOVERNMENT RESEARCH PROJECT FINAL REPORT, DONGGUK UNIVERSITY, KOREA, 30 March 2022 (2022-03-30), Korea, pages 1 - 31, XP009548913
KIM, S. A. ET AL.: "Preventive effect of a medicinal herb against 4-vinylcyclohexene diepoxide-induced ovotoxicity", 2021 INTERNATIONAL CONFERENCE OF THE KOREAN SOCIETY FOR MOLECULAR AND CELLULAR BIOLOGY, 5 November 2021 (2021-11-05)
LEE, JU-HEE: "Screening of medicinal herb enhancing ovarian function and analysis of its therapeutic effect against infertility", GOVERNMENT RESEARCH PROJECT FINAL REPORT, DONGGUK UNIVERSITY, KOREA, 30 March 2022 (2022-03-30), Korea, pages 1 - 31, XP009548913
KIM, S. A. ET AL.: "Preventive effect of a medicinal herb against 4-vinylcyclohexene diepoxide-induced ovotoxicity", 2021 INTERNATIONAL CONFERENCE OF THE KOREAN SOCIETY FOR MOLECULAR AND CELLULAR BIOLOGY, 5 November 2021 (2021-11-05)
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
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